Definitions for position effect
po·si·tion ef·fect

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1. position effectnoun

   (genetics) the effect on the expression of a gene that is produced by changing its location in a chromosome

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1. Position effect

   Position effect is the effect on the expression of a gene when its location in a chromosome is changed, often by translocation. This has been well described in Drosophila with respect to eye color and is known as position effect variegation (PEV).The phenotype is well characterised by unstable expression of a gene that results in the red eye coloration. In the mutant flies the eyes typically have a mottled appearance of white and red sectors. These phenotypes are often due to a chromosomal translocation such that the color gene is now close to a region of heterochromatin. Regions of heterochromatin can spread and influence transcription, which may result in the cessation of gene expression and subsequently, white eye sectors. Position effect is also used to describe the variation of expression exhibited by identical transgenes that insert into different regions of a genome. In this case the difference in expression is often due to enhancers that regulate neighboring genes. These local enhancers can also affect the expression pattern of the transgene. Since each transgenic organism has the transgene in a different location each transgenic organism has the potential for a unique expression pattern.

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1. position effect

   Position effect refers to the phenomenon in genetics where the physical position of a gene on a chromosome or within the genome influences its expression or mutation rate. The change in expression can occur due to the gene being moved to a new location (as in chromosomal translocation), or due to changes in nearby genes or regulatory regions. Thus, the same gene can behave differently depending on its position.

FreebaseRate this definition:0.0 / 0 votes

1. Position effect

   Position effect is the effect on the expression of a gene when its location in a chromosome is changed, often by translocation. This has been well described in Drosophila with respect to eye color and is known as position effect variegation. The phenotype is well characterised by unstable expression of a gene that results in the red eye coloration. In the mutant flies the eyes typically have a mottled appearance of white and red sectors. These phenotypes are often due to a chromosomal translocation such that the color gene is now close to a region of heterochromatin. The heterochromatin can spread stochastically and switch off the color gene resulting in the white eye sectors. Position effect is also used to describe the variation of expression exhibited by identical transgenes that insert into different regions of a genome. In this case the difference in expression is often due to enhancers that regulate neighboring genes. These local enhancers can also affect the expression pattern of the transgene. Since each transgenic organism has the transgene in a different location each transgenic organism has the potential for a unique expression pattern.

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1. • Consequence
   • Genetics

How to pronounce position effect?

1. Alex

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How to say position effect in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of position effect in Chaldean Numerology is: 6

2. Pythagorean Numerology

   The numerical value of position effect in Pythagorean Numerology is: 9