Definitions for optogenetics
op·to·ge·net·ics

WiktionaryRate this definition:0.0 / 0 votes

1. optogeneticsnoun

   A science that combines optics and genetics to probe neural circuits

2. Etymology: : (2006) Coined from optics and genetics by Karl Deisseroth and Mark J. Schnitzer in a review paper (K. Deisseroth, G. Feng, A. K. Majewska, G. Miesenböck, A. Ting, M. J. Schnitzer, Next-Generation Optical Technologies for Illuminating Genetically Targeted Brain Circuits, Journal of Neuroscience, vol. 26, no. 41 (October 2006), pp. 10380–6).

WikipediaRate this definition:0.0 / 0 votes

1. Optogenetics

   Optogenetics is a biological technique to control the activity of neurons or other cell types with light. This is achieved by expression of light-sensitive ion channels, pumps or enzymes specifically in the target cells. On the level of individual cells, light-activated enzymes and transcription factors allow precise control of biochemical signaling pathways. In systems neuroscience, the ability to control the activity of a genetically defined set of neurons has been used to understand their contribution to decision making, learning, fear memory, mating, addiction, feeding, and locomotion. In a first medical application of optogenetic technology, vision was partially restored in a blind patient.Optogenetic techniques have also been introduced to map the functional connectivity of the brain. By altering the activity of genetically labelled neurons with light and using imaging and electrophysiology techniques to record the activity of other cells, researchers can identify the statistical dependencies between cells and brain regions.In a broader sense, optogenetics also includes methods to record cellular activity with genetically encoded indicators. In 2010, optogenetics was chosen as the "Method of the Year" across all fields of science and engineering by the interdisciplinary research journal Nature Methods. At the same time, optogenetics was highlighted in the article on "Breakthroughs of the Decade" in the academic research journal Science.

WikidataRate this definition:0.0 / 0 votes

1. Optogenetics

   Optogenetics is a neuromodulation technique employed in neuroscience that uses a combination of techniques from optics and genetics to control the activity of individual neurons in living tissue—even within freely-moving animals—and to precisely measure the effects of those manipulations in real-time. The earliest approaches, now Waynflete Professor of Physiology at the University of Oxford, and Richard Kramer and Ehud Isacoff at the University of California, Berkeley conferred light sensitivity but were never reported to be useful by other laboratories due to the multiple components these approaches required. A distinct single-component approach involving microbial opsin genes introduced in 2005 turned out to be widely applied as described below. Optogenetics is known for the high spatial and temporal resolution that it provides in altering the activity of specific types of neurons within defined brain areas to control a subject's behavior. In 2010 Karl Deisseroth at Stanford University was awarded the inaugural HFSP Nakasone Award "for his pioneering work on the development of optogenetic methods for studying the function of neuronal networks underlying behavior."

How to pronounce optogenetics?

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Numerology

1. Chaldean Numerology

   The numerical value of optogenetics in Chaldean Numerology is: 1

2. Pythagorean Numerology

   The numerical value of optogenetics in Pythagorean Numerology is: 4

References

1. ^ Wiktionary
   https://en.wiktionary.org/wiki/Optogenetics
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Optogenetics
3. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=optogenetics