What does opsonin mean?
Definitions for opsonin
ˈɒp sə nɪnop·sonin
This dictionary definitions page includes all the possible meanings, example usage and translations of the word opsonin.
Princeton's WordNet
opsoninnoun
an antibody in blood serum that attaches to invading microorganisms and other antigens to make them more susceptible to the action of phagocytes
Wiktionary
opsoninnoun
Any antibody that causes an invading species to be more susceptible to phagocytosis
Wikipedia
Opsonin
Opsonins are extracellular proteins that, when bound to substances or cells, induce phagocytes to phagocytose the substances or cells with the opsonins bound. Thus, opsonins act as tags to label things in the body that should be phagocytosed (i.e. eaten) by phagocytes (cells that specialise in phagocytosis, i.e. cellular eating). Different types of things ("targets") can be tagged by opsonins for phagocytosis, including: pathogens (such as bacteria), cancer cells, aged cells, dead or dying cells (such as apoptotic cells), excess synapses, or protein aggregates (such as amyloid plaques). Opsonins help clear pathogens, as well as dead, dying and diseased cells.Opsonins were discovered and named "opsonins" in 1904 by Wright and Douglas, who found that incubating bacteria with blood plasma enabled phagocytes to phagocytose (and thereby destroy) the bacteria. They concluded that: “We have here conclusive proof that the blood fluids modify the bacteria in a manner which renders them a ready prey to the phagocytes. We may speak of this as an “opsonic” effect (opsono - I cater for; I prepare victuals for), and we may employ the term “opsonins” to designate the elements in the blood fluids which produce this effect.”Subsequent research found two main types of opsonin in blood that opsonised bacteria: complement proteins and antibodies. However, there are now known to be at least 50 proteins that act as opsonins for pathogens or other targets.
ChatGPT
opsonin
An opsonin is a molecule, typically an antibody or complement, that binds with foreign particles or pathogens, such as bacteria or viruses, and promotes their destruction or removal by white blood cells. It enhances the immune system's response to pathogens by making them more recognizable and thus more susceptible to phagocytosis, which is a process in which cells, such as macrophages and neutrophils, engulf and destroy the foreign particles.
Wikidata
Opsonin
An opsonin, is any molecule that enhances phagocytosis by marking an antigen for an immune response. However, the term is usually used in reference to molecules that act as a binding enhancer for the process of phagocytosis, especially antibodies, which coat the negatively charged molecules on the membrane. Molecules that activate the complement system are also considered opsonins. Phagocytic cells do not have an Fc receptor for IgM, making IgM ineffective in assisting phagocytosis. However, IgM is extremely efficient at activating complement and is, therefore, considered an opsonin. Opsonins can also refer to molecules that target a cell for destruction through the action of natural killer cells.
Matched Categories
Numerology
Chaldean Numerology
The numerical value of opsonin in Chaldean Numerology is: 9
Pythagorean Numerology
The numerical value of opsonin in Pythagorean Numerology is: 3
Translations for opsonin
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"opsonin." Definitions.net. STANDS4 LLC, 2024. Web. 25 Apr. 2024. <https://www.definitions.net/definition/opsonin>.
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