Definitions for ondansetron
on·dansetron

WiktionaryRate this definition:0.0 / 0 votes

1. ondansetronnoun

   A serotonin 5-HT3 receptor antagonist used mainly as an antiemetic to treat nausea and vomiting following chemotherapy.

WikipediaRate this definition:0.0 / 0 votes

1. Ondansetron

   Ondansetron, sold under the brand name Zofran among others, is a medication used to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy, or surgery. It is also effective for treating gastroenteritis. It can be given by mouth or by injection into a muscle or into a vein.Common side effects include diarrhea, constipation, headache, sleepiness, and itchiness. Serious side effects include QT prolongation and severe allergic reaction. It appears to be safe during pregnancy but has not been well studied in this group. It is a serotonin 5-HT3 receptor antagonist. It does not have any effect on dopamine receptors or muscarinic receptors.Ondansetron was patented in 1984 and approved for medical use in 1990. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication. In 2020, it was the 83rd most commonly prescribed medication in the United States, with more than 8 million prescriptions.

FreebaseRate this definition:0.0 / 0 votes

1. Ondansetron

   Ondansetron is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic, often following chemotherapy. It affects both peripheral and central nerves. Ondansetron reduces the activity of the vagus nerve, which deactivates the vomiting center in the medulla oblongata, and also blocks serotonin receptors in the chemoreceptor trigger zone. It has little effect on vomiting caused by motion sickness, and does not have any effect on dopamine receptors or muscarinic receptors.

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. Ondansetron

   A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.

How to pronounce ondansetron?

1. Alex

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   David

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   Mark

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   Daniel

   British

   Libby

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   Karen

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   Neerja

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Numerology

1. Chaldean Numerology

   The numerical value of ondansetron in Chaldean Numerology is: 3

2. Pythagorean Numerology

   The numerical value of ondansetron in Pythagorean Numerology is: 4

Examples of ondansetron in a Sentence

1. Obstetrics Gynecology:

   I think it's also important to keep in mind that the risks of any medication -- whether it's ondansetron or any other medication -- need to be balanced against the risks of inadequate treatment or no treatment, particularly in those patients that have severe nausea and vomiting in pregnancy, or hyperemesis gravidarum, those conditions carry some real risks themselves -- dehydration, electrolyte abnormalities -- and a lot of these patients require admission to the hospital if they're not adequately treated.

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