What does nigericin mean?
Definitions for nigericin
ni·gericin
This dictionary definitions page includes all the possible meanings, example usage and translations of the word nigericin.
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Wiktionary
nigericinnoun
An antibiotic, similar to monensin, obtained from Streptomyces hygroscopicus
Wikipedia
Nigericin
Nigericin is an antibiotic derived from Streptomyces hygroscopicus. Its isolation was described in the 1950s, and in 1968 the structure could be elucidated by X-ray crystallography. The structure and properties of nigericin are similar to the antibiotic monensin. Commercially it is obtained as a byproduct, or contaminant, at the fermentation of Geldanamycin. It is also called Polyetherin A, Azalomycin M, Helixin C, Antibiotic K178, Antibiotic X-464. Nigericin acts as an H+, K+, Pb2+ ionophore. Most commonly it is an antiporter of H+ and K+. In the past nigericin was used as an antibiotic active against gram positive bacteria. It inhibits the Golgi functions in Eukaryotic cells. Its ability to induce K+ efflux also makes it a potent activator of the NLRP3 inflammasome
Wikidata
Nigericin
Nigericin is an antibiotic derived from Streptomyces hygroscopicus. Its isolation was described in the 1950s, and in 1968 the structure could be elucidated by X-ray crystallography. The structure and properties of nigericin are similar to the antibiotic monensin. Commercially it is obtained as a byproduct, or contaminant, at the fermentation of Geldanamycin. It is also called Polyetherin A, Azalomycin M, Helixin C, Antibiotic K178, Antibiotic X-464. Nigericin acts as an H+, K+, Pb2+ ionophore. Most commonly it is an antiporter of H+ and K+. In the past nigericin was used as an antibiotic active against gram positive bacteria. It inhibits the Golgi functions in Eukaryotic cells. Nigericin exhibits anti-HIV activity.
U.S. National Library of Medicine
Nigericin
A polyether antibiotic which affects ion transport and ATPase activity in mitochondria. It is produced by Streptomyces hygroscopicus. (From Merck Index, 11th ed)
Numerology
Chaldean Numerology
The numerical value of nigericin in Chaldean Numerology is: 8
Pythagorean Numerology
The numerical value of nigericin in Pythagorean Numerology is: 7
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"nigericin." Definitions.net. STANDS4 LLC, 2025. Web. 14 Jan. 2025. <https://www.definitions.net/definition/nigericin>.
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