Definitions for nicardipine
nicardip·ine

WiktionaryRate this definition:0.0 / 0 votes

1. nicardipinenoun

   A calcium channel blocker used to treat high blood pressure and angina.

WikipediaRate this definition:0.0 / 0 votes

1. Nicardipine

   Nicardipine (Cardene) is a medication used to treat high blood pressure and angina. It belongs to the dihydropyridine class of calcium channel blockers (CCBs). It is also used for Raynaud's phenomenon. It is available in by mouth and intravenous formulations. It has been used in percutaneous coronary intervention.Its mechanism of action and clinical effects closely resemble those of nifedipine and the other dihydropyridine calcium channel blockers (amlodipine, felodipine), except that nicardipine is more selective for cerebral and coronary blood vessels. It is primarily a peripheral arterial vasodilator, thus unlike the nitrovasodilators (nitroglycerin and nitroprusside), cardiac preload is minimally affected. It has the longest duration among parenteral CCBs. As its use may lead to reflex tachycardia, it is advisable to use it in conjunction with a beta-blocker.It was patented in 1973 and approved for medical use in 1981.Nicardipine was approved by the FDA in December 1988. The patent for both Cardene and Cardene SR expired in October 1995.

WikidataRate this definition:0.0 / 0 votes

1. Nicardipine

   Nicardipine hydrochloride is a medication used to treat high blood pressure and angina. It belongs to the class of calcium channel blockers. Nicardipine is a dihydropyridine calcium-channel blocking agent used for the treatment of vascular disorders such as chronic stable angina, hypertension, and Raynaud's phenomenon. It is available in oral and intravenous formulations. Its mechanism of action and clinical effects closely resemble those of nifedipine and the other dihydropyridines, except that nicardipine is more selective for cerebral and coronary blood vessels. Furthermore, nicardipine does not intrinsically decrease myocardial contractility and may be useful in the management of congestive heart failure. Nicardipine also has a longer half-life than nifedipine. Nicardipine was approved by the FDA in December 1988. The patent for both Cardene and Cardene SR expired in October 1995. It has been used in percutaneous coronary intervention. Nicardipine is also an option for lowering of blood pressure in stroke patients who require blood pressure lowering prior to administration of Alteplase when blood pressure is >185/110. Also may be used during rtPA therapy when blood pressure is >230/120.

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. Nicardipine

   A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.

How to pronounce nicardipine?

1. Alex

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   Neerja

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Numerology

1. Chaldean Numerology

   The numerical value of nicardipine in Chaldean Numerology is: 9

2. Pythagorean Numerology

   The numerical value of nicardipine in Pythagorean Numerology is: 3

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References

1. ^ Wiktionary
   https://en.wiktionary.org/wiki/Nicardipine
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Nicardipine
3. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=nicardipine