Definitions for neutravidin
neu·tra·vidin

WiktionaryRate this definition:0.0 / 0 votes

1. neutravidinnoun

   A deglycosylated version of avidin

WikipediaRate this definition:0.0 / 0 votes

1. NeutrAvidin

   NeutrAvidin protein is a deglycosylated version of chicken avidin, with a mass of approximately 60,000 daltons. As a result of carbohydrate removal, lectin binding is reduced to undetectable levels, yet biotin binding affinity is retained because the carbohydrate is not necessary for this activity. Avidin has a high pI but NeutrAvidin has a near-neutral pI (pH 6.3), minimizing non-specific interactions with the negatively-charged cell surface or with DNA/RNA. Neutravidin still has lysine residues that remain available for derivatization or conjugation. Like avidin itself, NeutrAvidin is a tetramer with a strong affinity for biotin (Kd = 10−15 M). In biochemical applications, streptavidin, which also binds very tightly to biotin, may be used interchangeably with NeutrAvidin. Avidin immobilized onto solid supports is also used as purification media to capture biotin-labelled protein or nucleic acid molecules. For example, cell surface proteins can be specifically labelled with membrane-impermeable biotin reagent, then specifically captured using a NeutrAvidin support.

WikidataRate this definition:0.0 / 0 votes

1. NeutrAvidin

   NeutrAvidin protein is a deglycosylated version of avidin, with a mass of approximately 60,000 daltons. As a result of carbohydrate removal, lectin binding is reduced to undetectable levels, yet biotin binding affinity is retained because the carbohydrate is not necessary for this activity. Avidin has a high pI but NeutrAvidin has a near-neutral pI, minimizing non-specific interactions with the negatively charged cell surface or with DNA/RNA. Neutravidin still has lysine residues that remain available for derivatization or conjugation. Like avidin itself, NeutrAvidin is a tetramer with a strong affinity for biotin. In biochemical applications, streptavidin, which also binds very tightly to biotin, may be used interchangeably with NeutrAvidin. Avidin immobilized onto solid supports is also used as purification media to capture biotin-labelled protein or nucleic acid molecules. For example, cell surface proteins can be specifically labelled with membrane-impermeable biotin reagent, then specifically captured using a NeutrAvidin support.

How to pronounce neutravidin?

1. Alex

   US English

   David

   US English

   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

   British

   Fred

   US English

   Tessa

   South African

How to say neutravidin in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of neutravidin in Chaldean Numerology is: 4

2. Pythagorean Numerology

   The numerical value of neutravidin in Pythagorean Numerology is: 2

References

1. ^ Wiktionary
   https://en.wiktionary.org/wiki/Neutravidin
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Neutravidin
3. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=neutravidin