Definitions for minimisation
min·imi·sa·tion

Princeton's WordNetRate this definition:0.0 / 0 votes

1. minimization, minimisationnoun

   the act of reducing something to the least possible amount or degree or position

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1. minimisation

   Minimisation is a problem-solving or decision-making strategy in which the goal is to decrease, reduce, or minimise the value, cost, or quantity of a particular variable or set of variables to the smallest possible degree, often within a set of given constraints. This can be applicable in numerous fields such as mathematics, economics, computer science, and psychology.

WikidataRate this definition:0.0 / 0 votes

1. Minimisation

   Minimisation is a method of adaptive stratified sampling that is used in clinical trials, as described by Pocock and Simon. The aim of minimisation is to minimise the imbalance between the number of patients in each treatment group over a number of factors. Normally patients would be allocated to a treatment group randomly and while this maintains a good overall balance, it can lead to imbalances within sub-groups. For example if a majority of the patients who were receiving the active drug happened to be male, or smokers, the statistical usefulness of the study would be reduced. The traditional method to avoid this problem, known as blocked randomisation, is to stratify patients according to a number of factors and to use a separate randomisation list for each group. Each randomisation list would be created such that after every block of x patients, there would be an equal number in each treatment group. The problem with this method is that the number of lists increases exponentially with the number of stratification factors. Minimisation addresses this problem by calculating the imbalance within each factor should the patient be allocated to a particular treatment group. The various imbalances are added together to give the overall imbalance in the study. The treatment group that would minimise the imbalance can be chosen directly, or a random element may be added.

Matched Categories

1. • Reduction

How to pronounce minimisation?

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How to say minimisation in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of minimisation in Chaldean Numerology is: 1

2. Pythagorean Numerology

   The numerical value of minimisation in Pythagorean Numerology is: 1

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References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=minimisation
2. ^ ChatGPT
   https://chat.openai.com
3. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=minimisation