Definitions for microdialysis
mi·cro·dia·ly·sis

WiktionaryRate this definition:0.0 / 0 votes

1. microdialysisnoun

   A technique in which a short length of dialysis membrane is introduced into a biological tissue in order to collect samples of fluid for analysis.

WikipediaRate this definition:0.0 / 0 votes

1. Microdialysis

   Microdialysis is a minimally-invasive sampling technique that is used for continuous measurement of free, unbound analyte concentrations in the extracellular fluid of virtually any tissue. Analytes may include endogenous molecules (e.g. neurotransmitter, hormones, glucose, etc.) to assess their biochemical functions in the body, or exogenous compounds (e.g. pharmaceuticals) to determine their distribution within the body. The microdialysis technique requires the insertion of a small microdialysis catheter (also referred to as microdialysis probe) into the tissue of interest. The microdialysis probe is designed to mimic a blood capillary and consists of a shaft with a semipermeable hollow fiber membrane at its tip, which is connected to inlet and outlet tubing. The probe is continuously perfused with an aqueous solution (perfusate) that closely resembles the (ionic) composition of the surrounding tissue fluid at a low flow rate of approximately 0.1-5μL/min. Once inserted into the tissue or (body)fluid of interest, small solutes can cross the semipermeable membrane by passive diffusion. The direction of the analyte flow is determined by the respective concentration gradient and allows the usage of microdialysis probes as sampling as well as delivery tools. The solution leaving the probe (dialysate) is collected at certain time intervals for analysis.

WikidataRate this definition:0.0 / 0 votes

1. Microdialysis

   Microdialysis is a minimally-invasive sampling technique that is used for continuous measurement of free, unbound analyte concentrations in the extracellular fluid of virtually any tissue. For the procedure to be carried out, small amounts of brains chemical solutions are collected. Analytes may include endogenous molecules to assess their biochemical functions in the body, or exogenous compounds to determine their distribution within the body. The microdialysis technique requires the insertion of a small microdialysis catheter into the tissue of interest. The microdialysis probe is designed to mimic a blood capillary and consists of a shaft with a semipermeable hollow fiber membrane at its tip, which is connected to inlet and outlet tubing. The probe is continuously perfused with an aqueous solution that closely resembles the composition of the surrounding tissue fluid at a low flow rate of approximately 0.1-5μL/min. Once inserted into the tissue or fluid of interest, small solutes can cross the semipermeable membrane by passive diffusion. The direction of the analyte flow is determined by the respective concentration gradient and allows the usage of microdialysis probes as sampling as well as delivery tools. The solution leaving the probe is collected at certain time intervals for analysis.

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. Microdialysis

   A technique for measuring extracellular concentrations of substances in tissues, usually in vivo, by means of a small probe equipped with a semipermeable membrane. Substances may also be introduced into the extracellular space through the membrane.

How to pronounce microdialysis?

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Numerology

1. Chaldean Numerology

   The numerical value of microdialysis in Chaldean Numerology is: 7

2. Pythagorean Numerology

   The numerical value of microdialysis in Pythagorean Numerology is: 3

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References

1. ^ Wiktionary
   https://en.wiktionary.org/wiki/Microdialysis
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Microdialysis
3. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=microdialysis