Definitions for metformin
met·formin

Princeton's WordNetRate this definition:0.0 / 0 votes

1. metformin, Glucophagenoun

   an antidiabetic drug (trade name Glucophage) prescribed to treat type II diabetes

WiktionaryRate this definition:0.0 / 0 votes

1. metforminnoun

   [[Category:en:Drugs]]A popular oral drug for the treatment of diabetes, having the chemical formula CHN

WikipediaRate this definition:0.0 / 0 votes

1. Metformin

   Metformin, sold under the brand name Glucophage, among others, is the main first-line medication for the treatment of type 2 diabetes, particularly in people who are overweight. It is also used in the treatment of polycystic ovary syndrome. It is not associated with weight gain and is taken by mouth. It is sometimes used as an off-label adjunct to lessen the risk of metabolic syndrome in people who take antipsychotics.Metformin is generally well tolerated. Common adverse effects include diarrhea, nausea, and abdominal pain. It has a small risk of causing low blood sugar. High blood lactic acid level is a concern if the medication is used in overly large doses or prescribed in people with severe kidney problems. It is not recommended in those with significant liver disease. Metformin is a biguanide antihyperglycemic agent. It works by decreasing glucose production in the liver, increasing the insulin sensitivity of body tissues, and increasing GDF15 secretion, which reduces appetite and caloric intake.Metformin was discovered in 1922. French physician Jean Sterne began the study in humans in the 1950s. It was introduced as a medication in France in 1957 and the United States in 1995. It is on the World Health Organization's List of Essential Medicines. Metformin is the most widely used medication for diabetes taken by mouth. It is available as a generic medication. In 2020, it was the third most-commonly prescribed medication in the United States, with more than 92 million prescriptions.

ChatGPTRate this definition:0.0 / 0 votes

1. metformin

   Metformin is a prescription medication used primarily to control blood sugar levels in individuals with type 2 diabetes. This medicine belongs to a class of drugs known as biguanides, which work by reducing the amount of glucose produced by the liver and improving insulin sensitivity, thereby preventing the pancreas from releasing excessive amounts of insulin. It is often used in combination with a healthy diet and regular exercise to manage diabetes effectively. In some cases, it can also be used to treat polycystic ovary syndrome (PCOS).

WikidataRate this definition:0.0 / 0 votes

1. Metformin

   Metformin is an oral antidiabetic drug in the biguanide class. It is the first-line drug of choice for the treatment of type 2 diabetes, in particular, in overweight and obese people and those with normal kidney function. Its use in gestational diabetes has been limited by safety concerns. It is also used in the treatment of polycystic ovary syndrome, and has been investigated for other diseases where insulin resistance may be an important factor. Metformin works by suppressing glucose production by the liver. Metformin is the only antidiabetic drug that has been conclusively shown to prevent the cardiovascular complications of diabetes. It helps reduce LDL cholesterol and triglyceride levels, and is not associated with weight gain. As of 2010, metformin is one of only two oral antidiabetics in the World Health Organization Model List of Essential Medicines. When prescribed appropriately, metformin causes few adverse effects and is associated with a low risk of hypoglycemia. Lactic acidosis can be a serious concern in overdose and when it is prescribed to people with contraindications, but otherwise, there is no significant risk.

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. Metformin

   A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)

Matched Categories

1. • Antidiabetic

How to pronounce metformin?

1. Alex

   US English

   David

   US English

   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

   British

   Fred

   US English

   Tessa

   South African

How to say metformin in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of metformin in Chaldean Numerology is: 4

2. Pythagorean Numerology

   The numerical value of metformin in Pythagorean Numerology is: 5

Examples of metformin in a Sentence

1. Nir Barzilai:

   We kind of know what are the main nodes that have to happen for the body to be resilient to stresses and be able to live longer. They include pathways like the insulin signaling pathway or the growth pathway and some other mechanisms, it happens that this drug, metformin, works on several of those mechanisms that are so crucial to stop the aging process— glucose being one of them but not a central one.

2. Janet Woodcock:

   The FDA is investigating whether metformin in the U.S. market contains NDMA, and whether it is above the acceptable daily intake limit of 96 nanograms.

3. Anoop Misra:

   Metformin could be especially useful in people who are unable to follow diet and exercise strictly, who are obese, have polycystic ovarian disease, or can not walk or exercise due to physical infirmity, it is a low cost drug, and could be useful in underprivileged populations also.

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References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=metformin
2. ^ Wiktionary
   https://en.wiktionary.org/wiki/Metformin
3. ^ Wikipedia
   https://en.wikipedia.org/wiki/Metformin
4. ^ ChatGPT
   https://chat.openai.com
5. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=metformin