What does metallothionein mean?
Definitions for metallothionein
met·al·loth·ionein
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Wiktionary
metallothioneinnoun
Any of a family of cysteine-rich proteins that bond to heavy metals
Wikidata
Metallothionein
Metallothionein is a family of cysteine-rich, low molecular weight proteins. They are localized to the membrane of the Golgi apparatus. MTs have the capacity to bind both physiological and xenobiotic heavy metals through the thiol group of its cysteine residues, which represents nearly the 30% of its amino acidic residues. MT was discovered in 1957 by Vallee and Margoshe from purification of a Cd-binding protein from horse renal cortex. MTs function is not clear, but experimental data suggest MTs may provide protection against metal toxicity, be involved in regulation of physiological metals and provide protection against oxidative stress. There are four main isoforms expressed in humans: MT1, MT2, MT3, MT4. In the human body, large quantities are synthesised primarily in the liver and kidneys. Their production is dependent on availability of the dietary minerals, as zinc, copper and selenium, and the amino acids histidine and cysteine.
U.S. National Library of Medicine
Metallothionein
A low-molecular-weight (approx. 10 kD) protein occurring in the cytoplasm of kidney cortex and liver. It is rich in cysteinyl residues and contains no aromatic amino acids. Metallothionein shows high affinity for bivalent heavy metals.
Numerology
Chaldean Numerology
The numerical value of metallothionein in Chaldean Numerology is: 6
Pythagorean Numerology
The numerical value of metallothionein in Pythagorean Numerology is: 1
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"metallothionein." Definitions.net. STANDS4 LLC, 2024. Web. 18 Apr. 2024. <https://www.definitions.net/definition/metallothionein>.
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