What does metabolon mean?
Definitions for metabolon
metabolon
This dictionary definitions page includes all the possible meanings, example usage and translations of the word metabolon.
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Wikidata
Metabolon
A metabolon is a temporary structural-functional complex formed between sequential enzymes of a metabolic pathway, held together by noncovalent interactions, and structural elements of the cell such as integral membrane proteins and proteins of the cytoskeleton. The concept of structural-metabolic cellular complexes was first conceived in 1970 by A. M. Kuzin of the USSR Academy of Sciences, and adopted in 1972 by P. A. Srere of the University of Texas for the enzymes of the Tricarboxilic Acids Cycle. This hypothesis was well accepted in the former USSR and further developed for the complex of glycolytic enzymes by B.I. Kurganov and A.E. Lyubarev. In the middle 70’s the group of F.M. Clarke at the University of Queensland, Australia also worked on the concept. The name “METABOLON” was first proposed in 1985 by P. Srere during a lecture in Debrecen, Hungary. The formation of metabolons allows passing the intermediary metabolic product from an enzyme directly as substrate into the active site of the consecutive enzyme of the metabolic pathway. The Kreb's Cycle is an example of a metabolon which facilitates substrate channeling. During the functioning of metabolons the amount of water needed to hydrate the enzymes is reduced and the enzyme activity is increased.
CrunchBase
Metabolon
Metabolon, Inc., a technology company, develops analytical methods and software for biomarker discovery using metabolomics. It offers biochemical profiling platform that analyzes and identifies biochemicals in the research of pharmaceutical, biotech, agriculture, cosmetic, and consumer products. The company provides biochemical markers and information for understanding biochemical processes, such as drug action, toxicology, and bioprocess monitoring. Its metabolomics platform is used to develop diagnostics for cancer, amyotropic lateral sclerosis, diabetes, and metabolic diseases. The company was founded in 2000 and is based in Durham, North Carolina.
Numerology
Chaldean Numerology
The numerical value of metabolon in Chaldean Numerology is: 2
Pythagorean Numerology
The numerical value of metabolon in Pythagorean Numerology is: 7
Translations for metabolon
From our Multilingual Translation Dictionary
- métabolismeFrench
- metabolonPortuguese
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"metabolon." Definitions.net. STANDS4 LLC, 2024. Web. 19 Apr. 2024. <https://www.definitions.net/definition/metabolon>.
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