Definitions for meperidine
məˈpɛr ɪˌdin, -dɪnmeperi·dine

Princeton's WordNetRate this definition:0.0 / 0 votes

1. meperidine, meperidine hydrochloride, Demerolnoun

   a synthetic narcotic drug (trade name Demerol) used to treat pain

WiktionaryRate this definition:0.0 / 0 votes

1. meperidinenoun

   The opioid analgesic drug pethidine (INN).

WikipediaRate this definition:0.0 / 0 votes

1. meperidine

   Pethidine, also known as meperidine and sold under the brand name Demerol among others, is a synthetic opioid pain medication of the phenylpiperidine class. Synthesized in 1938 as a potential anticholinergic agent by the German chemist Otto Eisleb, its analgesic properties were first recognized by Otto Schaumann while working for IG Farben, Germany. Pethidine is the prototype of a large family of analgesics including the pethidine 4-phenylpiperidines (piminodine, anileridine and others), the prodines (alphaprodine, MPPP, etc.), bemidones (ketobemidone, etc.) and others more distant, including diphenoxylate and analogues.Pethidine is indicated for the treatment of moderate to severe pain, and is delivered as a hydrochloride salt in tablets, as a syrup, or by intramuscular, subcutaneous, or intravenous injection. For much of the 20th century, pethidine was the opioid of choice for many physicians; in 1975, 60% of doctors prescribed it for acute pain and 22% for chronic severe pain.It was patented in 1937 and approved for medical use in 1943. Compared with morphine, pethidine was thought to be safer, carry a lower risk of addiction, and to be superior in treating the pain associated with biliary spasm or renal colic due to its putative anticholinergic effects. These were later discovered to be inaccurate assumptions, as it carries an equal risk of addiction, possesses no advantageous effects on biliary spasm or renal colic compared to other opioids, and due to its toxic metabolite, norpethidine, it is more toxic than other opioids—especially during long-term use. The norpethidine metabolite was found to have serotonergic effects, so pethidine could, unlike most opioids, contribute to serotonin syndrome.

ChatGPTRate this definition:0.0 / 0 votes

1. meperidine

   Meperidine is a prescription medication belonging to the class of drugs called opioid analgesics. It's primarily used to help relieve moderate to severe pain by altering the way the brain and nervous system respond to pain. It is also sometimes used to help put patients to sleep before an operation and enhance the effects of certain types of anesthesia. Commonly known under the brand name Demerol, meperidine has potential for misuse and addiction, and should only be used under a healthcare professional's supervision.

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. Meperidine

   A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.

Matched Categories

1. • Narcotic

How to pronounce meperidine?

1. Alex

   US English

   David

   US English

   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

   British

   Fred

   US English

   Tessa

   South African

How to say meperidine in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of meperidine in Chaldean Numerology is: 4

2. Pythagorean Numerology

   The numerical value of meperidine in Pythagorean Numerology is: 8

Popularity rank by frequency of use

References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=meperidine
2. ^ Wiktionary
   https://en.wiktionary.org/wiki/Meperidine
3. ^ Wikipedia
   https://en.wikipedia.org/wiki/Meperidine
4. ^ ChatGPT
   https://chat.openai.com