What does megalocephaly mean?

Definitions for megalocephaly

This dictionary definitions page includes all the possible meanings, example usage and translations of the word megalocephaly.

Princeton's WordNet

  1. macrocephaly, megacephaly, megalocephalynoun

    an abnormally large head; differs from hydrocephalus because there is no increased intracranial pressure and the overgrowth is symmetrical


  1. megalocephaly

    Megalencephaly (or macrencephaly; abbreviated MEG) is a growth development disorder in which the brain is abnormally large. It is characterized by a brain with an average weight that is 2.5 standard deviations above the mean of the general population. Approximately 1 out of 50 children (2%) are said to have the characteristics of megalencephaly in the general population.A mutation in the PI3K-AKT pathway is believed to be the primary cause of brain proliferation and ultimately the root cause of megalencephaly. This mutation has produced a classification of brain overdevelopment that consists of two syndromes including megalencephaly-capillary malformation (MCAP) and megalencephaly-polydactyly-polymicrogyria-hydrocephalus (MPPH). Megalencephaly is usually diagnosed at birth and is confirmed with an MRI. There are several neuropsychiatric disorders linked with megalencephaly; however, studies have shown that autism is the most prevalent association with the malformation of MEG. Although no treatment currently exists for megalencephaly, management methods are focused at reducing deficits linked with autism. Most recent research is targeted at creating inhibitors to reduce the mutational pathway that causes megalencephaly.


  1. megalocephaly

    Megalocephaly, also known as macrocephaly, is a medical condition characterized by an abnormally large, oversized head circumference. This is typically due to an increased size of the brain, caused by underlying conditions such as genetic disorders, metabolic diseases, or neurologic abnormalities. The enlarged head size can be present at birth or it may develop during the first few years of life.


  1. Megalocephaly

    Macrocephaly, occurs when the head is abnormally large ; this includes the scalp, the cranial bone, and the contents of the cranium.

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  1. Chaldean Numerology

    The numerical value of megalocephaly in Chaldean Numerology is: 4

  2. Pythagorean Numerology

    The numerical value of megalocephaly in Pythagorean Numerology is: 6


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"megalocephaly." Definitions.net. STANDS4 LLC, 2023. Web. 10 Dec. 2023. <https://www.definitions.net/definition/megalocephaly>.

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