What does map kinase signaling system mean?

Definitions for map kinase signaling system
map ki·nase sig·nal·ing sys·tem

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U.S. National Library of Medicine

  1. MAP Kinase Signaling System

    An intracellular signaling system involving the MAP kinase cascades (three-membered protein kinase cascades). Various upstream activators, which act in response to extracellular stimuli, trigger the cascades by activating the first member of a cascade, MAP KINASE KINASE KINASES; (MAPKKKs). Activated MAPKKKs phosphorylate MITOGEN-ACTIVATED PROTEIN KINASE KINASES which in turn phosphorylate the MITOGEN-ACTIVATED PROTEIN KINASES; (MAPKs). The MAPKs then act on various downstream targets to affect gene expression. In mammals, there are several distinct MAP kinase pathways including the ERK (extracellular signal-regulated kinase) pathway, the SAPK/JNK (stress-activated protein kinase/c-jun kinase) pathway, and the p38 kinase pathway. There is some sharing of components among the pathways depending on which stimulus originates activation of the cascade.

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Numerology

  1. Chaldean Numerology

    The numerical value of map kinase signaling system in Chaldean Numerology is: 3

  2. Pythagorean Numerology

    The numerical value of map kinase signaling system in Pythagorean Numerology is: 3


Translations for map kinase signaling system

From our Multilingual Translation Dictionary

  • carte système de signalisation de la kinaseFrench

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"map kinase signaling system." Definitions.net. STANDS4 LLC, 2024. Web. 24 Apr. 2024. <https://www.definitions.net/definition/map+kinase+signaling+system>.

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