What does lysophosphatidylcholine mean?
Definitions for lysophosphatidylcholine
lysophos·phatidyl·choline
This dictionary definitions page includes all the possible meanings, example usage and translations of the word lysophosphatidylcholine.
Wiktionary
lysophosphatidylcholinenoun
Any derivative of phosphatidylcholine in which one or both acyl derivatives have been removed by hydrolysis
Wikipedia
Lysophosphatidylcholine
Lysophosphatidylcholines (LPC, lysoPC), also called lysolecithins, are a class of chemical compounds which are derived from phosphatidylcholines.
Wikidata
Lysophosphatidylcholine
Lysophosphatidylcholines, also called lysolecithins, are a class of chemical compounds which are derived from phosphatidylcholines. They result from partial hydrolysis of phosphatidylcholines, which removes one of the fatty acid groups. The hydrolysis is generally the result of the enzymatic action of phospholipase A2. LPC can be used in the lab to cause demyelination of brain slices, to mimic the effects of demyelinating diseases such as multiple sclerosis. Among other properties, they stimulate phagocytosis of the myelin sheath and can change the surface properties of erythrocytes. LPC-induced demyelination is thought to occur through the actions of recruited macrophages and microglia which phagocytose nearby myelin. Invading T cells are also thought to mediate this process. LPC is present as a minor phospholipid in the cell membrane and in the blood plasma. Since LPCs are quickly metabolized by lysophospholipase and LPC-acyltransferase, they last only shortly in vivo. By replacing the acyl-group within the LPC with an alkyl-group, alkyl-lysophospholipids were synthesized. These analogues of LPC are metabolically stable, and several such as edelfosine, miltefosine and perifosine are under research and development as drugs against cancer and other diseases.
Numerology
Chaldean Numerology
The numerical value of lysophosphatidylcholine in Chaldean Numerology is: 3
Pythagorean Numerology
The numerical value of lysophosphatidylcholine in Pythagorean Numerology is: 2
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"lysophosphatidylcholine." Definitions.net. STANDS4 LLC, 2024. Web. 18 Apr. 2024. <https://www.definitions.net/definition/lysophosphatidylcholine>.
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