Definitions for lorfan
lor·fan

Princeton's WordNetRate this definition:0.0 / 0 votes

1. levallorphan, Lorfannoun

   drug (trade name Lorfan) that is related to morphine but that counteracts the respiratory depression produced by morphine poisoning but without affecting its analgesic effects

WikipediaRate this definition:0.0 / 0 votes

1. lorfan

   Levallorphan (INN, BAN) (brand names Lorfan, Naloxifan, Naloxiphan), also known as levallorphan tartrate (USAN), is an opioid modulator of the morphinan family used as an opioid analgesic and opioid antagonist/antidote. It acts as an antagonist of the μ-opioid receptor (MOR) and as an agonist of the κ-opioid receptor (KOR), and as a result, blocks the effects of stronger agents with greater intrinsic activity such as morphine whilst simultaneously producing analgesia.Levallorphan was formerly widely used in general anesthesia, mainly to reverse the respiratory depression produced by opioid analgesics and barbiturates used for induction of surgical anaesthesia whilst maintaining a degree of analgesia (via KOR agonism). It is now less commonly employed for this purpose as the newer drug naloxone tends to be used instead. Levallorphan was also used in combination with opioid analgesics to reduce their side effects, mainly in obstetrics, and a very small dose of levallorphan used alongside a full agonist of the MOR can produce greater analgesia than when the latter is used by itself. The combination of levallorphan with pethidine (meperidine) was indeed used so frequently, a standardized formulation was made available, known as Pethilorfan.As an agonist of the KOR, levallorphan can produce severe mental reactions at sufficient doses including hallucinations, dissociation, and other psychotomimetic effects, dysphoria, anxiety, confusion, dizziness, disorientation, derealization, feelings of drunkenness, delusions, paranoia, and bizarre, unusual, or disturbing dreams.

ChatGPTRate this definition:0.0 / 0 votes

1. lorfan

   Lorfan is a term used in the pharmaceutical industry to refer to a drug that is intended for the treatment of a rare disease or disorder. These drugs are often developed for conditions that affect a small number of people, making them less profitable for drug companies to research and produce. However, providing treatments for rare diseases is important for improving the quality of life for those affected by these conditions.

How to pronounce lorfan?

1. Alex

   US English

   David

   US English

   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

   British

   Fred

   US English

   Tessa

   South African

How to say lorfan in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of lorfan in Chaldean Numerology is: 8

2. Pythagorean Numerology

   The numerical value of lorfan in Pythagorean Numerology is: 3

References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=lorfan
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Lorfan
3. ^ ChatGPT
   https://chat.openai.com