What does lipidation mean?

Definitions for lipidation
lip·i·da·tion

This dictionary definitions page includes all the possible meanings, example usage and translations of the word lipidation.


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Wiktionary

  1. lipidationnoun

    modification (especially of a protein) by association with a lipid

Wikipedia

  1. lipidation

    Lipid-anchored proteins (also known as lipid-linked proteins) are proteins located on the surface of the cell membrane that are covalently attached to lipids embedded within the cell membrane. These proteins insert and assume a place in the bilayer structure of the membrane alongside the similar fatty acid tails. The lipid-anchored protein can be located on either side of the cell membrane. Thus, the lipid serves to anchor the protein to the cell membrane. They are a type of proteolipids. The lipid groups play a role in protein interaction and can contribute to the function of the protein to which it is attached. Furthermore, the lipid serves as a mediator of membrane associations or as a determinant for specific protein-protein interactions. For example, lipid groups can play an important role in increasing molecular hydrophobicity. This allows for the interaction of proteins with cellular membranes and protein domains. In a dynamic role, lipidation can sequester a protein away from its substrate to inactivate the protein and then activate it by substrate presentation. Overall, there are three main types of lipid-anchored proteins which include prenylated proteins, fatty acylated proteins and glycosylphosphatidylinositol-linked proteins (GPI). A protein can have multiple lipid groups covalently attached to it, but the site where the lipids bind to the protein depends both on the lipid group and protein.

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Numerology

  1. Chaldean Numerology

    The numerical value of lipidation in Chaldean Numerology is: 8

  2. Pythagorean Numerology

    The numerical value of lipidation in Pythagorean Numerology is: 1


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"lipidation." Definitions.net. STANDS4 LLC, 2024. Web. 25 Apr. 2024. <https://www.definitions.net/definition/lipidation>.

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