What does linkage (genetics) mean?
Definitions for linkage (genetics)
linkage (ge·netics)
This dictionary definitions page includes all the possible meanings, example usage and translations of the word linkage (genetics).
Wikipedia
linkage (genetics)
Genetic linkage is the tendency of DNA sequences that are close together on a chromosome to be inherited together during the meiosis phase of sexual reproduction. Two genetic markers that are physically near to each other are unlikely to be separated onto different chromatids during chromosomal crossover, and are therefore said to be more linked than markers that are far apart. In other words, the nearer two genes are on a chromosome, the lower the chance of recombination between them, and the more likely they are to be inherited together. Markers on different chromosomes are perfectly unlinked, although the penetrance of potentially deleterious alleles may be influenced by the presence of other alleles, and these other alleles may be located on other chromosomes than that on which a particular potentially deleterious allele is located.Genetic linkage is the most prominent exception to Gregor Mendel's Law of Independent Assortment. The first experiment to demonstrate linkage was carried out in 1905. At the time, the reason why certain traits tend to be inherited together was unknown. Later work revealed that genes are physical structures related by physical distance. The typical unit of genetic linkage is the centimorgan (cM). A distance of 1 cM between two markers means that the markers are separated to different chromosomes on average once per 100 meiotic product, thus once per 50 meioses.
U.S. National Library of Medicine
Linkage (Genetics)
The association in inheritance of two or more non-allelic GENES due to their being located more or less closely on the same CHROMOSOME.
Numerology
Chaldean Numerology
The numerical value of linkage (genetics) in Chaldean Numerology is: 4
Pythagorean Numerology
The numerical value of linkage (genetics) in Pythagorean Numerology is: 6
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