Definitions for linezolid
line·zol·id

WiktionaryRate this definition:0.0 / 0 votes

1. linezolidnoun

   A synthetic antibiotic of the oxazolidinone class.

WikipediaRate this definition:0.0 / 0 votes

1. Linezolid

   Linezolid is an antibiotic used for the treatment of infections caused by Gram-positive bacteria that are resistant to other antibiotics. Linezolid is active against most Gram-positive bacteria that cause disease, including streptococci, vancomycin-resistant enterococci (VRE), and methicillin-resistant Staphylococcus aureus (MRSA). The main uses are infections of the skin and pneumonia although it may be used for a variety of other infections including drug-resistant tuberculosis. It is used either by injection into a vein or by mouth.When given for short periods, linezolid is a relatively safe antibiotic. It can be used in people of all ages and in people with liver disease or poor kidney function. Common side effects with short-term use include headache, diarrhea, rash, and nausea. Serious side effects may include serotonin syndrome, bone marrow suppression, and high blood lactate levels, particularly when used for more than two weeks. If used for longer periods it may cause nerve damage, including optic nerve damage, which may be irreversible.As a protein synthesis inhibitor, linezolid works by suppressing bacterial protein production. This either stops growth or results in bacterial death. Although many antibiotics work this way, the exact mechanism of action of linezolid appears to be unique in that it blocks the initiation of protein production, rather than one of the later steps. As of 2014, bacterial resistance to linezolid has remained low. Linezolid is a member of the oxazolidinone class of medications.Linezolid was discovered in the mid-1990s, and was approved for commercial use in 2000. It is on the World Health Organization's List of Essential Medicines. The World Health Organization classifies linezolid as critically important for human medicine. Linezolid is available as a generic medication.

WikidataRate this definition:0.0 / 0 votes

1. Linezolid

   Linezolid is a synthetic antibiotic developed by a team at Pharmacia and Upjohn Company. It is used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics. A member of the oxazolidinone class of drugs, linezolid is active against most Gram-positive bacteria that cause disease, including streptococci, vancomycin-resistant enterococci, and methicillin-resistant Staphylococcus aureus. The main indications of linezolid are infections of the skin and soft tissues and pneumonia, although off-label use for a variety of other infections is becoming popular. Linezolid is marketed by Pfizer under the trade names Zyvox, Zyvoxid, and Zyvoxam. Generics are also available, such as Linospan and Arlin and Linospan in Pakistan, by Nucleus. Discovered in the 1990s and first approved for use in 2000, linezolid was the first commercially available 1,3-oxazolidinone antibiotic. As of 2009, it is the only marketed oxazolidinone, although others are in development. As a protein synthesis inhibitor, it stops the growth of bacteria by disrupting their production of proteins. Although many antibiotics work this way, the exact mechanism of action of linezolid appears to be unique in that it blocks the initiation of protein production, and not one of the later steps. Bacterial resistance to linezolid has remained very low since it was first detected in 1999, although it may be increasing.

How to pronounce linezolid?

1. Alex

   US English

   David

   US English

   Mark

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   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

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   Fred

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   Tessa

   South African

How to say linezolid in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of linezolid in Chaldean Numerology is: 9

2. Pythagorean Numerology

   The numerical value of linezolid in Pythagorean Numerology is: 7

Popularity rank by frequency of use

References

1. ^ Wiktionary
   https://en.wiktionary.org/wiki/Linezolid
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Linezolid
3. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=linezolid