What does in vivo mean?
Definitions for in vivo
ɪn ˈvi voʊin vi·vo
This dictionary definitions page includes all the possible meanings, example usage and translations of the word in vivo.
Princeton's WordNet
in vivoadverb
within a living organism
"in vivo techniques"
in vivoadverb
in the living organism
"studies conducted in vivo"
Wiktionary
in vivoadverb
Within a living organism.
in vivoadjective
Within a living organism.
Etymology: Borrowed from.
Wikipedia
In vivo
Studies that are in vivo (Latin for "within the living"; often not italicized in English) are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, and plants, as opposed to a tissue extract or dead organism. This is not to be confused with experiments done in vitro ("within the glass"), i.e., in a laboratory environment using test tubes, Petri dishes, etc. Examples of investigations in vivo include: the pathogenesis of disease by comparing the effects of bacterial infection with the effects of purified bacterial toxins; the development of non-antibiotics, antiviral drugs, and new drugs generally; and new surgical procedures. Consequently, animal testing and clinical trials are major elements of in vivo research. In vivo testing is often employed over in vitro because it is better suited for observing the overall effects of an experiment on a living subject. In drug discovery, for example, verification of efficacy in vivo is crucial, because in vitro assays can sometimes yield misleading results with drug candidate molecules that are irrelevant in vivo (e.g., because such molecules cannot reach their site of in vivo action, for example as a result of rapid catabolism in the liver).The English microbiologist Professor Harry Smith and his colleagues in the mid-1950s found that sterile filtrates of serum from animals infected with Bacillus anthracis were lethal for other animals, whereas extracts of culture fluid from the same organism grown in vitro were not. This discovery of anthrax toxin through the use of in vivo experiments had a major impact on studies of the pathogenesis of infectious disease. The maxim in vivo veritas ("in a living thing [there is] truth") is a play on in vino veritas, ("in wine [there is] truth"), a well-known proverb.
ChatGPT
in vivo
"In vivo" is a Latin term that means "within the living". It refers to various experiments, procedures, or observations performed or made inside the living organism itself, often in a natural biological context. This could include studies on cells in their natural location within the body of an organism, drug testing in live subjects, or any other biological process occurring in the actual life form rather than in a controlled or artificial laboratory environment like in a test tube or petri dish (known as in vitro).
Wikidata
In vivo
In vivo is experimentation using a whole, living organism as opposed to a partial or dead organism, or an in vitro controlled environment. Animal testing and clinical trials are two forms of in vivo research. In vivo testing is often employed over in vitro because it is better suited for observing the overall effects of an experiment on a living subject. The maxim in vivo veritas used to describe this type of testing is a play on words from in vino veritas, in wine [there is] truth.
Numerology
Chaldean Numerology
The numerical value of in vivo in Chaldean Numerology is: 8
Pythagorean Numerology
The numerical value of in vivo in Pythagorean Numerology is: 1
Examples of in vivo in a Sentence
By forming this alliance each company will be looking to leverage the others' advantages in different regions, with Xiaomi's strong user base in India, Vivo and Oppo in Southeast Asia, and Huawei in Europe, secondly, it's to start to build some more negotiation power against Google.
By making it simple for developers to increase their reach across multiple app stores, Huawei, Oppo, Vivo, and Xiaomi stand to attract more developers and, ultimately, more apps.
We will now move forward to going into in-vivo studies, maybe with mice or hamsters or other animals that can be used as a model for COVID 19 disease, but the next step after that we really can't say.
You can find online a preprint, non-peer-reviewed paper that seems to suggest that in vitro, in other words in test tubes, that there is some antiviral activity for this compound, but I can tell you there are millions of compounds that, when tested in vitro, in a test tube, appear to have some antiviral activity but that are worthless in vivo, in humans.
What’s been developed before has either been for ex vivo tissue analysis, with solvents that are not compatible, or using high pressure nitrogen or high voltage that’s not compatible with living tissue.
Translations for in vivo
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"in vivo." Definitions.net. STANDS4 LLC, 2024. Web. 24 Apr. 2024. <https://www.definitions.net/definition/in+vivo>.
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