What does immune evasion mean?

Definitions for immune evasion
im·mune eva·sion

This dictionary definitions page includes all the possible meanings, example usage and translations of the word immune evasion.


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Wikipedia

  1. immune evasion

    Antigenic escape, immune escape, immune evasion or escape mutation occurs when the immune system of a host, especially of a human being, is unable to respond to an infectious agent: the host's immune system is no longer able to recognize and eliminate a pathogen, such as a virus. This process can occur in a number of different ways of both a genetic and an environmental nature. Such mechanisms include homologous recombination, and manipulation and resistance of the host's immune responses.Different antigens are able to escape through a variety of mechanisms. For example, the African trypanosome parasites are able to clear the host's antibodies, as well as resist lysis and inhibit parts of the innate immune response. A bacteria, Bordetella pertussis, is able to escape the immune response by inhibiting neutrophils and macrophages from invading the infection site early on. One cause of antigenic escape is that a pathogen's epitopes (the binding sites for immune cells) become too similar to a person's naturally occurring MHC-1 epitopes, resulting in the immune system becoming unable to distinguish the infection from self-cells. Antigenic escape is not only crucial for the host's natural immune response, but also for the resistance against vaccinations. The problem of antigenic escape has greatly deterred the process of creating new vaccines. Because vaccines generally cover a small ratio of strains of one virus, the recombination of antigenic DNA that lead to diverse pathogens allows these invaders to resist even newly developed vaccinations. Some antigens may even target pathways different from those the vaccine had originally intended to target. Recent research on many vaccines, including the malaria vaccine, has focused on how to anticipate this diversity and create vaccinations that can cover a broader spectrum of antigenic variation. On 12 May 2021, scientists reported to The United States Congress of the continuing threat of COVID-19 variants and COVID-19 escape mutations, such as the E484K virus mutation.

U.S. National Library of Medicine

  1. Immune Evasion

    Methods used by pathogenic organisms to evade a host's immune system.

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Numerology

  1. Chaldean Numerology

    The numerical value of immune evasion in Chaldean Numerology is: 8

  2. Pythagorean Numerology

    The numerical value of immune evasion in Pythagorean Numerology is: 7

Examples of immune evasion in a Sentence

  1. Anthony Fauci:

    That will give you a pretty good idea as to what the level of immune evasion is. That process will take likely two weeks or more, perhaps even sooner, depending upon how well the virus grows in the isolates that we get, and in those countries in which there are a lot of cases like South Africa, the computational biologists and the evolutionary biologists are going to be getting a good feel as to what the competition of this virus would be with Delta. Those are just a few of the things that will take a couple of weeks to a few weeks to learn.


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"immune evasion." Definitions.net. STANDS4 LLC, 2024. Web. 19 Apr. 2024. <https://www.definitions.net/definition/immune+evasion>.

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