What does ic50 mean?

Definitions for ic50
ic50

Here are all the possible meanings and translations of the word ic50.


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Wiktionary

  1. IC50abbreviation

    The concentration of an inhibitor that is required for 50-percent inhibition of an enzyme in vitro.

Freebase

  1. IC50

    The half maximal inhibitory concentration is a measure of the effectiveness of a compound in inhibiting biological or biochemical function. This quantitative measure indicates how much of a particular drug or other substance is needed to inhibit a given biological process by half. In other words, it is the half maximal inhibitory concentration of a substance. It is commonly used as a measure of antagonist drug potency in pharmacological research. According to the FDA, IC50 represents the concentration of a drug that is required for 50% inhibition in vitro. It is comparable to an EC50 for agonist drugs. EC50 also represents the plasma concentration required for obtaining 50% of a maximum effect in vivo.

Editors Contribution

  1. IC50

    IC 50 is the dose of the drug required to kill 50%of cancer cells.The smaller the IC 50, more potent the drug is. Drugs having large IC50 can be toxic and can have side effects.

    IC50 is given to patients only in critical conditions.

    Submitted by anonymous on March 15, 2019  

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Numerology

  1. Chaldean Numerology

    The numerical value of ic50 in Chaldean Numerology is: 4

  2. Pythagorean Numerology

    The numerical value of ic50 in Pythagorean Numerology is: 3

Images & Illustrations of ic50

  1. ic50ic50ic50ic50ic50


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    a state of irritation or annoyance
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