The concentration of an inhibitor that is required for 50-percent inhibition of an enzyme in vitro.
The half maximal inhibitory concentration is a measure of the effectiveness of a compound in inhibiting biological or biochemical function. This quantitative measure indicates how much of a particular drug or other substance is needed to inhibit a given biological process by half. In other words, it is the half maximal inhibitory concentration of a substance. It is commonly used as a measure of antagonist drug potency in pharmacological research. According to the FDA, IC50 represents the concentration of a drug that is required for 50% inhibition in vitro. It is comparable to an EC50 for agonist drugs. EC50 also represents the plasma concentration required for obtaining 50% of a maximum effect in vivo.
IC 50 is the dose of the drug required to kill 50%of cancer cells.The smaller the IC 50more potent the drug is.Drugs having large IC50 can be toxic and can have side effects.
The numerical value of ic50 in Chaldean Numerology is: 4
The numerical value of ic50 in Pythagorean Numerology is: 3
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