What does hmgn mean?
Definitions for hmgn
hmgn
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Wikipedia
HMGN
HMGN (High Mobility Group Nucleosome-binding) proteins are members of the broader class of high mobility group (HMG) chromosomal proteins that are involved in regulation of transcription, replication, recombination, and DNA repair. HMGN1 and HMGN2 (initially designated HMG-14 and HMG-17 respectively) were discovered by E.W. Johns research group in the early 1970s. HMGN3, HMGN4, and HMGN5 were discovered later and are less abundant. HMGNs are nucleosome binding proteins that help in transcription, replication, recombination, and DNA repair. They can also alter the chromatin epigenetic landscape, helping to stabilize cell identity. There is still relatively little known about their structure and function. HMGN proteins are found in all vertebrates, and play a role in chromatin structure and histone modification. HMGNs come in long chains of amino acids, containing around 100 for HMGN1-4, and roughly 200 in HMGN5. Recent research on the HMGN family is focused on their effect on cell identity, and how reduction of HMGNs relates to induced reprogramming of mouse embryonic fibroblasts (MEFs).
Wikidata
HMGN
HMGN stands for High Mobility Group Nucleosome-binding. HMGN proteins are members of the broader class of High mobility group chromosomal proteins that help in transcription, replication, recombination, and DNA repair. Though identified more than 30 years back, little is known about the actual role of these basic proteins. There are several types of HMGN proteins; N1, N2, N3, N4 & N5. Many of these are conserved among the higher eukaryotes. HMGNs are non-histone proteins, which associate with nucleosomes to control transcription of genes. HMGNs control transcription by altering the interaction of histone H1 with nucleosomes to maintain a decondensed chromatin structure.
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HMGN
What does HMGN stand for? -- Explore the various meanings for the HMGN acronym on the Abbreviations.com website.
Numerology
Chaldean Numerology
The numerical value of hmgn in Chaldean Numerology is: 8
Pythagorean Numerology
The numerical value of hmgn in Pythagorean Numerology is: 6
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"hmgn." Definitions.net. STANDS4 LLC, 2024. Web. 19 Apr. 2024. <https://www.definitions.net/definition/hmgn>.
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