What does histocompatibility antigens class i mean?

Definitions for histocompatibility antigens class i
his·to·com·pat·i·bil·i·ty anti·gen·s class i

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Wikipedia

  1. histocompatibility antigens class i

    MHC class I molecules are one of two primary classes of major histocompatibility complex (MHC) molecules (the other being MHC class II) and are found on the cell surface of all nucleated cells in the bodies of vertebrates. They also occur on platelets, but not on red blood cells. Their function is to display peptide fragments of proteins from within the cell to cytotoxic T cells; this will trigger an immediate response from the immune system against a particular non-self antigen displayed with the help of an MHC class I protein. Because MHC class I molecules present peptides derived from cytosolic proteins, the pathway of MHC class I presentation is often called cytosolic or endogenous pathway.In humans, the HLAs corresponding to MHC class I are HLA-A, HLA-B, and HLA-C.

U.S. National Library of Medicine

  1. Histocompatibility Antigens Class I

    Large transmembrane, polymorphic glycoproteins noncovalently associated with nonpolymorphic beta 2-microglobulin. In humans, three structural genes on chromosome 6 code for the HLA-A; HLA-B and HLA-C antigens. In mice, three genes named K, D, and L on chromosome 17 code for the H-2 antigens. Class I antigens are found on most nucleated cells and are generally detected by their reactivity with alloantisera. These antigens are recognized during graft rejection and restrict cell-mediated lysis of virus-infected cells. They are primarily associated with rheumatologic diseases and certain malignant disorders.

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Numerology

  1. Chaldean Numerology

    The numerical value of histocompatibility antigens class i in Chaldean Numerology is: 2

  2. Pythagorean Numerology

    The numerical value of histocompatibility antigens class i in Pythagorean Numerology is: 8

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"histocompatibility antigens class i." Definitions.net. STANDS4 LLC, 2024. Web. 25 Apr. 2024. <https://www.definitions.net/definition/histocompatibility+antigens+class+i>.

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