What does hemosiderin mean?

Definitions for hemosiderin
hemosiderin

This dictionary definitions page includes all the possible meanings, example usage and translations of the word hemosiderin.

Princeton's WordNet

  1. hemosiderin, haemosiderinnoun

    a granular brown substance composed of ferric oxide; left from the breakdown of hemoglobin; can be a sign of disturbed iron metabolism

GCIDE

  1. hemosiderinnoun

    a granular yellowish-brown substance composed of protein and ferric oxide, resulting from the breakdown of hemoglobin; it has a higher iron content than ferritin, and its presence in body tissues or phagocytes can be a symptom of disturbed iron metabolism.

Wiktionary

  1. hemosiderinnoun

    An abnormal microscopic pigment, formed of granules of a complex of iron hydroxides, protein and polysaccharides, that forms in tissues of patients having an excess of iron

Wikipedia

  1. Hemosiderin

    Hemosiderin or haemosiderin is an iron-storage complex that is composed of partially digested ferritin and lysosomes. The breakdown of heme gives rise to biliverdin and iron. The body then traps the released iron and stores it as hemosiderin in tissues. Hemosiderin is also generated from the abnormal metabolic pathway of ferritin.It is only found within cells (as opposed to circulating in blood) and appears to be a complex of ferritin, denatured ferritin and other material. The iron within deposits of hemosiderin is very poorly available to supply iron when needed. Hemosiderin can be identified histologically with Perls' Prussian blue stain; iron in hemosiderin turns blue to black when exposed to potassium ferrocyanide. In normal animals, hemosiderin deposits are small and commonly inapparent without special stains. Excessive accumulation of hemosiderin is usually detected within cells of the mononuclear phagocyte system (MPS) or occasionally within epithelial cells of the liver and kidney. Several disease processes result in deposition of larger amounts of hemosiderin in tissues; although these deposits often cause no symptoms, they can lead to organ damage. Hemosiderin is most commonly found in macrophages and is especially abundant in situations following hemorrhage, suggesting that its formation may be related to phagocytosis of red blood cells and hemoglobin. Hemosiderin can accumulate in different organs in various diseases. Iron is required by many of the chemical reactions (i.e., oxidation-reduction reactions) in the body but is toxic when not properly contained. Thus, many methods of iron storage have developed.

ChatGPT

  1. hemosiderin

    Hemosiderin is a brownish-yellow, granular pigment that is produced as a byproduct of hemoglobin breakdown. It is an iron-storage complex found within cells, particularly in situations where excess iron is present in the body. The compound is considered as a marker for identifying conditions such as iron overload disorders or conditions involving cellular damage and subsequent breakdown of red blood cells.

Wikidata

  1. Hemosiderin

    Hemosiderin or haemosiderin is an iron-storage complex. It is always found within cells and appears to be a complex of ferritin, denatured ferritin and other material. The iron within deposits of hemosiderin is very poorly available to supply iron when needed. Several disease processes result in deposition of larger amounts of hemosiderin in tissues; although these deposits often cause no symptoms, they can lead to organ damage. Hemosiderin is most commonly found in macrophages and is especially abundant in situations following hemorrhage, suggesting that its formation may be related to phagocytosis of red blood cells and hemoglobin. Hemosiderin can accumulate in different organs in various diseases. Iron is required by many of the chemical reactions in the body but is toxic when not properly contained. Thus, many methods of iron storage have developed.

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Numerology

  1. Chaldean Numerology

    The numerical value of hemosiderin in Chaldean Numerology is: 6

  2. Pythagorean Numerology

    The numerical value of hemosiderin in Pythagorean Numerology is: 2


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"hemosiderin." Definitions.net. STANDS4 LLC, 2024. Web. 24 Apr. 2024. <https://www.definitions.net/definition/hemosiderin>.

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