What does glucocorticoid receptor mean?
Definitions for glucocorticoid receptor
glu·co·cor·ti·coid recep·tor
This dictionary definitions page includes all the possible meanings, example usage and translations of the word glucocorticoid receptor.
Wiktionary
glucocorticoid receptornoun
a protein found in multiple forms within cells, which binds glucocorticoids and subsequently influences gene transcription
Wikidata
Glucocorticoid receptor
The glucocorticoid receptor also known as NR3C1 is the receptor to which cortisol and other glucocorticoids bind. The GR is expressed in almost every cell in the body and regulates genes controlling the development, metabolism, and immune response. Because the receptor gene is expressed in several forms, it has many different effects in different parts of the body. When the GR binds to glucocorticoids, its primary mechanism of action is the regulation of gene transcription. The unbound receptor resides in the cytosol of the cell. After the receptor is bound to glucocorticoid, the receptor-glucorticoid complex can take either of two paths. The activated GR complex up-regulates the expression of anti-inflammatory proteins in the nucleus or represses the expression of pro-inflammatory proteins in the cytosol. In humans, the GR protein is encoded by NR3C1 gene which is located on chromosome 5.
Numerology
Chaldean Numerology
The numerical value of glucocorticoid receptor in Chaldean Numerology is: 9
Pythagorean Numerology
The numerical value of glucocorticoid receptor in Pythagorean Numerology is: 2
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"glucocorticoid receptor." Definitions.net. STANDS4 LLC, 2024. Web. 16 Apr. 2024. <https://www.definitions.net/definition/glucocorticoid+receptor>.
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