Definitions for glipizide
glip·izide

Princeton's WordNetRate this definition:0.0 / 0 votes

1. glipizide, Glucotrolnoun

   an oral antidiabetic drug (trade name Glucotrol) that stimulates the release of insulin from the pancreas

WiktionaryRate this definition:0.0 / 0 votes

1. glipizidenoun

   A sulfonylurea antidiabetic drug.

WikipediaRate this definition:0.0 / 0 votes

1. Glipizide

   Glipizide, sold under the brand name Glucotrol among others, is an anti-diabetic medication of the sulfonylurea class used to treat type 2 diabetes. It is used together with a diabetic diet and exercise. It is not indicated for use by itself in type 1 diabetes. It is taken by mouth. Effects generally begin within half an hour and can last for up to a day.Common side effects include nausea, diarrhea, low blood sugar, and headache. Other side effects include sleepiness, skin rash, and shakiness. The dose may need to be adjusted in those with liver or kidney disease. Use during pregnancy or breastfeeding is not recommended. It works by stimulating the pancreas to release insulin and increases tissue sensitivity to insulin.Glipizide was approved for medical use in the United States in 1984. It is available as a generic medication. In 2020, it was the 49th most commonly prescribed medication in the United States, with more than 13 million prescriptions.

FreebaseRate this definition:0.0 / 0 votes

1. Glipizide

   Glipizide is an oral rapid- and short-acting anti-diabetic drug from the sulfonylurea class. It is classified as a second generation sulfonylurea, which means that it undergoes enterohepatic circulation. Second-generation sulfonylureas are both more potent and have shorter half-lives than the first-generation sulfonylureas. Mechanism of action is produced by blocking potassium channels in the beta cells of the islets of Langerhans. By partially blocking the potassium channels, the cell remains depolarized, increasing the time the cell spends in the calcium release stage of cell, which results in signaling leading to calcium influx. The increase in calcium will initiate more insulin release from each beta cell. Sulfonylureas may also cause the decrease of serum glucagon and potentiate the action of insulin at the extrapancreatic tissues. Originally available in 1984, it is marketed by Pfizer under the brand name Glucotrol in the USA, where Pfizer sells Glucotrol in doses of 5 and 10 milligrams and Glucotrol XL in doses of 2.5, 5, and 10 milligrams. Other companies also market glipizide, most commonly extended release tablets of 5 and 10 milligrams.

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. Glipizide

   An oral hypoglycemic agent which is rapidly absorbed and completely metabolized.

Matched Categories

1. • Antidiabetic

How to pronounce glipizide?

1. Alex

   US English

   David

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   Mark

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   Daniel

   British

   Libby

   British

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   Karen

   Australian

   Hayley

   Australian

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   Indian

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   Neerja

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   Oliver

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   South African

How to say glipizide in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of glipizide in Chaldean Numerology is: 6

2. Pythagorean Numerology

   The numerical value of glipizide in Pythagorean Numerology is: 7

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