What does gliotoxin mean?
Definitions for gliotoxin
gliotox·in
This dictionary definitions page includes all the possible meanings, example usage and translations of the word gliotoxin.
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Wikidata
Gliotoxin
Gliotoxin is a sulfur-containing mycotoxin produced by several species of fungi, including pathogens of humans such as Aspergillus fumigatus, and also by species of Trichoderma, and Penicillium. Gliotoxin has also been reported from yeasts of the genus Candida, but results from other studies have cast doubt on the production of this metabolite by Candida fungi. Gliotoxin was originally isolated from Gliocladium fimbriatum, and was named accordingly. It is an epipolythiodioxopiperazine metabolite. Gliotoxin possesses immunosuppressive properties as it may suppress and cause apoptosis in certain types of cells of the immune system, including neutrophils, eosinophils, granulocytes, macrophages, and thymocytes. It also acts as an inhibitor of farnesyl transferase. It noncompetitively inhibits the chymotrypsin-like activity of the 20S proteasome. In vivo it displays anti-inflammatory activity. It acts by blocking thiol groups in the cell membranes. It was investigated as an antibiotic and antifungal in the 1940s and recently as an antiviral agent.
U.S. National Library of Medicine
Gliotoxin
A fungal toxin produced by various species of Trichoderma, Gladiocladium fimbriatum, Aspergillus fumigatus, and Penicillium. It is used as an immunosuppressive agent.
Numerology
Chaldean Numerology
The numerical value of gliotoxin in Chaldean Numerology is: 9
Pythagorean Numerology
The numerical value of gliotoxin in Pythagorean Numerology is: 8
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"gliotoxin." Definitions.net. STANDS4 LLC, 2024. Web. 24 Apr. 2024. <https://www.definitions.net/definition/gliotoxin>.
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