Definitions for ghrelin
ghre·lin

Princeton's WordNetRate this definition:0.0 / 0 votes

1. ghrelinnoun

   a gastrointestinal hormone produced by epithelial cells lining the fundus of the stomach; appears to be a stimulant for appetite and feeding, but is also a strong stimulant of growth hormone secretion from the anterior pituitary

WiktionaryRate this definition:0.0 / 0 votes

1. ghrelinnoun

   A peptide hormone, secreted in the stomach, that increases appetite.

2. Etymology: From acronym GHR +, a common hormone suffix. Incidental pun on ghre-.

WikipediaRate this definition:0.0 / 0 votes

1. Ghrelin

   Ghrelin (; or lenomorelin, INN) is a hormone produced by enteroendocrine cells of the gastrointestinal tract, especially the stomach, and is often called a "hunger hormone" because it increases the drive to eat. Blood levels of ghrelin are highest before meals when hungry, returning to lower levels after mealtimes. Ghrelin may help prepare for food intake by increasing gastric motility and stimulating the secretion of gastric acid.Ghrelin activates cells in the anterior pituitary gland and hypothalamic arcuate nucleus, including neuropeptide Y neurons that initiate appetite. Ghrelin stimulates brain structures having a specific receptor – the growth hormone secretagogue receptor 1A (GHSR-1A). Ghrelin also participates in regulation of reward cognition, learning and memory, the sleep-wake cycle, taste sensation, reward behavior, and glucose metabolism.

ChatGPTRate this definition:0.0 / 0 votes

1. ghrelin

   Ghrelin is a hormone produced by specialized cells that line the stomach and the pancreas. It is often termed the "hunger hormone" as it is responsible for stimulating the appetite and encouraging the body to consume more food and store more fat. In addition, ghrelin influences body energy use and plays a role in the regulation of growth hormone secretion from the pituitary gland. Its levels in the body fluctuate throughout the day, generally being highest before meals when hungry and lowest an hour after meals.

WikidataRate this definition:0.0 / 0 votes

1. Ghrelin

   Ghrelin is a 28 amino acid hunger-stimulating peptide and hormone that is produced mainly by P/D1 cells lining the fundus of the human stomach and epsilon cells of the pancreas. Ghrelin together with obestatin is produced from cleavage of the ghrelin/obestatin prepropeptide which in turn is encoded by the GHRL gene. Ghrelin receptors are expressed in a wide variety of tissues, including the pituitary, stomach, intestine, pancreas, thymus, gonads, thyroid, and heart. The diversity of ghrelin receptor locations suggests ghrelin has diverse biological functions. Ghrelin levels increase before meals and decrease after meals. It is considered the counterpart of the hormone leptin, produced by adipose tissue, which induces satiation when present at higher levels. In some bariatric procedures, the level of ghrelin is reduced in patients, thus causing satiation before it would normally occur. Ghrelin is a potent stimulator of growth hormone secretion from the anterior pituitary gland. The ghrelin receptor is a G protein-coupled receptor, known as the growth hormone secretagogue receptor. Ghrelin binds to the GHSR1a splice-variant of this receptor which is present in high density in the hypothalamus, pituitary as well as vagal afferent cell bodies and vagal afferent endings throughout the gastro-intestinal tract.

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. Ghrelin

   A 28-amino acid, acylated, orexigenic peptide that is a ligand for GROWTH HORMONE SECRETAGOGUE RECEPTORS. Ghrelin is widely expressed but primarily in the stomach in the adults. Ghrelin acts centrally to stimulate growth hormone secretion and food intake, and peripherally to regulate energy homeostasis. Its large precursor protein, known as appetite-regulating hormone or motilin-related peptide, contains ghrelin and obestatin.

Editors ContributionRate this definition:0.0 / 0 votes

1. ghrelin

   A type of natural hormone created in moderation within the body of a human being.

   Ghrelin has an effect on our body weight, energy balance and food desire.

   
   

   Submitted by MaryC on September 6, 2020  

Matched Categories

1. • Gastrointestinal Hormone

How to pronounce ghrelin?

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How to say ghrelin in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of ghrelin in Chaldean Numerology is: 6

2. Pythagorean Numerology

   The numerical value of ghrelin in Pythagorean Numerology is: 1

Examples of ghrelin in a Sentence

1. George Koob:

   Our hope is that down the line, we might be able to do a simple blood test that tells if you will be a naltrexone person, an acamprosate person, a ghrelin person.

2. Raj Dasgupta:

   The' g' in ghrelin stands for gain : This fast-acting hormone increases hunger and leads to weight gain.

3. Raj Dasgupta:

   The 'l' in leptin stands for lose: It suppresses appetite and therefore contributes to weight loss, the 'g' in ghrelin stands for gain: This fast-acting hormone increases hunger and leads to weight gain.

4. Alissa Rumsey:

   Too little sleep can lead to surging levels of ghrelin, a hormone that stimulates appetite, as well as decreased levels of leptin, a hormone that causes feelings of fullness.

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References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=ghrelin
2. ^ Wiktionary
   https://en.wiktionary.org/wiki/Ghrelin
3. ^ Wikipedia
   https://en.wikipedia.org/wiki/Ghrelin
4. ^ ChatGPT
   https://chat.openai.com
5. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=ghrelin