What does focal adhesions mean?

Definitions for focal adhesions
fo·cal ad·he·sions

This dictionary definitions page includes all the possible meanings, example usage and translations of the word focal adhesions.


  1. focal adhesions

    In cell biology, focal adhesions (also cell–matrix adhesions or FAs) are large macromolecular assemblies through which mechanical force and regulatory signals are transmitted between the extracellular matrix (ECM) and an interacting cell. More precisely, focal adhesions are the sub-cellular structures that mediate the regulatory effects (i.e., signaling events) of a cell in response to ECM adhesion.Focal adhesions serve as the mechanical linkages to the ECM, and as a biochemical signaling hub to concentrate and direct numerous signaling proteins at sites of integrin binding and clustering.

U.S. National Library of Medicine

  1. Focal Adhesions

    An anchoring junction of the cell to a non-cellular substrate. It is composed of a specialized area of the plasma membrane where bundles of MICROFILAMENTS terminate and attach to the transmembrane linkers, INTEGRINS, which in turn attach through their extracellular domains to EXTRACELLULAR MATRIX PROTEINS.

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  1. Chaldean Numerology

    The numerical value of focal adhesions in Chaldean Numerology is: 2

  2. Pythagorean Numerology

    The numerical value of focal adhesions in Pythagorean Numerology is: 5

Translations for focal adhesions

From our Multilingual Translation Dictionary

  • الالتصاقات البؤريةArabic

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"focal adhesions." Definitions.net. STANDS4 LLC, 2023. Web. 25 Sep. 2023. <https://www.definitions.net/definition/focal+adhesions>.

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