What does foam cell mean?
Definitions for foam cell
foam cell
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Wikipedia
Foam cell
Foam cells, also called lipid-laden macrophages, are a type of cell that contain cholesterol. These can form a plaque that can lead to atherosclerosis and trigger heart attacks and stroke.Foam cells are fat-laden cells with a M2 macrophage-like phenotype. They contain low density lipoproteins (LDL) and can only be truly detected by examining a fatty plaque under a microscope after it is removed from the body. They are named because the lipoproteins give the cell a foamy appearance.Despite the connection with cardiovascular diseases they might not be inherently dangerous.Some foam cells are derived from smooth muscle cells and present a limited macrophage-like phenotype.
Wikidata
Foam cell
Foam Cells are lipid-loaded macrophages that have surrounded large amounts of a fatty substance, usually cholesterol. These can be found in blood vessel walls that are crammed with fatty material. Macrophages are a type of immune cell. They are found in nearly all tissues in the body. They are produced by the division of monocytes. Foam cells are formed when the body sends macrophages to the location of a fatty deposit on the blood vessel walls. The macrophage surrounds the fatty material in an attempt to destroy it. The cell becomes filled with lipids. The lipids surrounded by the macrophage give it a “foamy” appearance. In chronic hyperlipidemia, lipoproteins aggregate within the intima of blood vessels and become oxidized by the action of oxygen free radicals generated either by macrophages or endothelial cells. The macrophages engulf oxidized low-density lipoproteins by endocytosis via scavenger receptors, which are distinct from LDL receptors. The oxidized LDL accumulates in the macrophages and other phagocytes, which are then known as foam cells. Foam cells form the fatty streaks of the plaques of atheroma in the tunica intima of arteries.
Numerology
Chaldean Numerology
The numerical value of foam cell in Chaldean Numerology is: 7
Pythagorean Numerology
The numerical value of foam cell in Pythagorean Numerology is: 4
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"foam cell." Definitions.net. STANDS4 LLC, 2024. Web. 25 Apr. 2024. <https://www.definitions.net/definition/foam+cell>.
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