What does fluocinolone mean?
Definitions for fluocinolone
flu·o·ci·nolone
This dictionary definitions page includes all the possible meanings, example usage and translations of the word fluocinolone.
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Wiktionary
fluocinolonenoun
A synthetic hydrocortisone derivative used in dermatology to reduce skin inflammation and relieve itching.
Wikidata
Fluocinolone
A synthetic glucocorticoid with anti-inflammatory and antipruritic activities. Fluocinolone binds the glucocorticoid receptor, followed by translocation of the ligand-receptor complex to the nucleus and transcription activation of genes containing glucocorticoid-responsive elements. Lipocortin-1 is one factor induced by fluocinolone that interacts with and inhibits cytosolic phospholipase 2 alpha, thereby preventing phospholipase translocation to the perinuclear membrane and subsequent release and conversion of arachidonic acid to inflammatory prostaglandins. In addition, MAPK phosphatase 1 is induced, thereby preventing the triggering of the MAPK cascade resulting in pro-inflammatory effects via Jun N-terminal kinase and c-Jun. Finally, fluocinolone binds to and inhibits nuclear factor kappa-B directly, resulting in inhibition of cyclooxygenase 2 transcription and subsequent prostaglandin synthesis.
Numerology
Chaldean Numerology
The numerical value of fluocinolone in Chaldean Numerology is: 6
Pythagorean Numerology
The numerical value of fluocinolone in Pythagorean Numerology is: 6
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"fluocinolone." Definitions.net. STANDS4 LLC, 2024. Web. 19 Apr. 2024. <https://www.definitions.net/definition/fluocinolone>.
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