What does fibronectin mean?
Definitions for fibronectin
fi·bronectin
This dictionary definitions page includes all the possible meanings, example usage and translations of the word fibronectin.
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Wiktionary
fibronectinnoun
An adhesive blood glycoprotein that has several cellular functions
Wikidata
Fibronectin
Fibronectin is a high-molecular weight glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. Similar to integrins, fibronectin binds extracellular matrix components such as collagen, fibrin, and heparan sulfate proteoglycans. Fibronectin exists as a protein dimer, consisting of two nearly identical monomers linked by a pair of disulfide bonds. The fibronectin protein is produced from a single gene, but alternative splicing of its pre-mRNA leads to the creation of several isoforms. Two types of fibronectin are present in vertebrates: ⁕soluble plasma fibronectin is a major protein component of blood plasma and is produced in the liver by hepatocytes. ⁕insoluble cellular fibronectin is a major component of the extracellular matrix. It is secreted by various cells, primarily fibroblasts, as a soluble protein dimer and is then assembled into an insoluble matrix in a complex cell-mediated process. Fibronectin plays a major role in cell adhesion, growth, migration, and differentiation, and it is important for processes such as wound healing and embryonic development. Altered fibronectin expression, degradation, and organization has been associated with a number of pathologies, including cancer and fibrosis.
Editors Contribution
fibronectin
Is a glycoprotein.
Fibronectin plays a major role in cell adhesion, growth, migration, and differentiation.
Submitted by MaryC on December 14, 2015
Numerology
Chaldean Numerology
The numerical value of fibronectin in Chaldean Numerology is: 7
Pythagorean Numerology
The numerical value of fibronectin in Pythagorean Numerology is: 7
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"fibronectin." Definitions.net. STANDS4 LLC, 2024. Web. 25 Apr. 2024. <https://www.definitions.net/definition/fibronectin>.
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