Definitions for fibrinogen
faɪˈbrɪn ə dʒənfib·rino·gen

Princeton's WordNetRate this definition:0.0 / 0 votes

1. fibrinogen, factor Inoun

   a protein present in blood plasma; converts to fibrin when blood clots

WiktionaryRate this definition:0.0 / 0 votes

1. fibrinogennoun

   A protein that in humans plays a part in the forming of clots.

WikipediaRate this definition:0.0 / 0 votes

1. Fibrinogen

   Fibrinogen (factor I) is a glycoprotein complex, produced in the liver, that circulates in the blood of all vertebrates. During tissue and vascular injury, it is converted enzymatically by thrombin to fibrin and then to a fibrin-based blood clot. Fibrin clots function primarily to occlude blood vessels to stop bleeding. Fibrin also binds and reduces the activity of thrombin. This activity, sometimes referred to as antithrombin I, limits clotting. Fibrin also mediates blood platelet and endothelial cell spreading, tissue fibroblast proliferation, capillary tube formation, and angiogenesis and thereby promotes revascularization and wound healing.Reduced and/or dysfunctional fibrinogens occur in various congenital and acquired human fibrinogen-related disorders. These disorders represent a group of rare conditions in which individuals may present with severe episodes of pathological bleeding and thrombosis; these conditions are treated by supplementing blood fibrinogen levels and inhibiting blood clotting, respectively. These disorders may also be the cause of certain liver and kidney diseases.Fibrinogen is a "positive" acute-phase protein, i.e. its blood levels rise in response to systemic inflammation, tissue injury, and certain other events. It is also elevated in various cancers. Elevated levels of fibrinogen in inflammation as well as cancer and other conditions have been suggested to be the cause of thrombosis and vascular injury that accompanies these conditions.

ChatGPTRate this definition:0.0 / 0 votes

1. fibrinogen

   Fibrinogen is a soluble protein present in vertebrate blood plasma which acts as a precursor to fibrin, responsible for the clotting or coagulation of blood. It gets converted into fibrin by the action of the enzyme, thrombin, during the blood clotting process. Its deficiency or malfunction can result in bleeding disorders.

Webster DictionaryRate this definition:0.0 / 0 votes

1. Fibrinogennoun

   an albuminous substance existing in the blood, and in other animal fluids, which either alone or with fibrinoplastin or paraglobulin forms fibrin, and thus causes coagulation

2. Etymology: [Fibrin + -gen.]

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. Fibrinogen

   Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.

Editors ContributionRate this definition:0.0 / 0 votes

1. fibrinogen

   A type of protein present in blood plasma.

   Fibrinogen is a precursor to fibrin.

   
   

   Submitted by MaryC on December 15, 2015  

EntomologyRate this definition:0.0 / 0 votes

1. Fibrinogen

   a proteid substance of the blood and other body fluids, concerned in the production of fibrin.

Matched Categories

1. • Coagulation Factor

How to pronounce fibrinogen?

1. Alex

   US English

   David

   US English

   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

   British

   Fred

   US English

   Tessa

   South African

How to say fibrinogen in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of fibrinogen in Chaldean Numerology is: 3

2. Pythagorean Numerology

   The numerical value of fibrinogen in Pythagorean Numerology is: 9

Popularity rank by frequency of use

References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=fibrinogen
2. ^ Wiktionary
   https://en.wiktionary.org/wiki/Fibrinogen
3. ^ Wikipedia
   https://en.wikipedia.org/wiki/Fibrinogen
4. ^ ChatGPT
   https://chat.openai.com
5. ^ Webster Dictionary
   https://www.merriam-webster.com/dictionary/fibrinogen
6. ^ Entomology
   https://www.gutenberg.org/files/22748/22748-h/22748-h.htm#:~:text=fibrinogen