Definitions for fanconi syndrome
fan·coni syn·drome

WikipediaRate this definition:0.0 / 0 votes

1. Fanconi syndrome

   Fanconi syndrome or Fanconi's syndrome (English: , ) is a syndrome of inadequate reabsorption in the proximal renal tubules of the kidney. The syndrome can be caused by various underlying congenital or acquired diseases, by toxicity (for example, from toxic heavy metals), or by adverse drug reactions. It results in various small molecules of metabolism being passed into the urine instead of being reabsorbed from the tubular fluid (for example, glucose, amino acids, uric acid, phosphate, and bicarbonate). Fanconi syndrome affects the proximal tubules, namely, the proximal convoluted tubule (PCT), which is the first part of the tubule to process fluid after it is filtered through the glomerulus, and the proximal straight tubule (pars recta), which leads to the descending limb of loop of Henle.Different forms of Fanconi syndrome can affect different functions of the proximal tubule, and result in different complications. The loss of bicarbonate results in type 2 or proximal renal tubular acidosis. The loss of phosphate results in the bone diseases rickets and osteomalacia (even with adequate vitamin D and calcium levels), because phosphate is necessary for bone development in children and even for ongoing bone metabolism in adults.

WikidataRate this definition:0.0 / 0 votes

1. Fanconi syndrome

   Fanconi syndrome is a disease of the proximal renal tubules of the kidney in which glucose, amino acids, uric acid, phosphate and bicarbonate are passed into the urine, instead of being reabsorbed. Fanconi syndrome affects the proximal tubule, which is the first part of the tubule to process fluid after it is filtered through the glomerulus. It may be inherited, or caused by drugs or heavy metals. Different forms of Fanconi syndrome can affect different functions of the proximal tubule, and result in different complications. The loss of bicarbonate results in type 2 or proximal renal tubular acidosis. The loss of phosphate results in the bone disease rickets, because phosphate is necessary for bone development.

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. Fanconi Syndrome

   A hereditary or acquired form of generalized dysfunction of the PROXIMAL KIDNEY TUBULE without primary involvement of the KIDNEY GLOMERULUS. It is usually characterized by the tubular wasting of nutrients and salts (GLUCOSE; AMINO ACIDS; PHOSPHATES; and BICARBONATES) resulting in HYPOKALEMIA; ACIDOSIS; HYPERCALCIURIA; and PROTEINURIA.

How to pronounce fanconi syndrome?

1. Alex

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   David

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   Mark

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   Daniel

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   Libby

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Numerology

1. Chaldean Numerology

   The numerical value of fanconi syndrome in Chaldean Numerology is: 7

2. Pythagorean Numerology

   The numerical value of fanconi syndrome in Pythagorean Numerology is: 4

References

1. ^ Wikipedia
   https://en.wikipedia.org/wiki/Fanconi_Syndrome
2. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=fanconi syndrome