What does exostoses, multiple hereditary mean?

Definitions for exostoses, multiple hereditary
ex·os·toses, mul·ti·ple hered·i·ta·ry

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Wikipedia

  1. exostoses, multiple hereditary

    Hereditary multiple osteochondromas (HMO), also known as hereditary multiple exostoses, is a disorder characterized by the development of multiple benign osteocartilaginous masses (exostoses) in relation to the ends of long bones of the lower limbs such as the femurs and tibias and of the upper limbs such as the humeri and forearm bones. They are also known as osteochondromas. Additional sites of occurrence include on flat bones such as the pelvic bone and scapula. The distribution and number of these exostoses show a wide diversity among affected individuals. Exostoses usually present during childhood. The vast majority of affected individuals become clinically manifest by the time they reach adolescence. A small percentage of affected individuals are at risk for development of sarcomas as a result of malignant transformation. The incidence of hereditary multiple exostoses is around 1 in 50,000 individuals. Hereditary multiple osteochondromas is the preferred term used by the World Health Organization.

U.S. National Library of Medicine

  1. Exostoses, Multiple Hereditary

    Hereditary disorder transmitted by an autosomal dominant gene and characterized by multiple exostoses (multiple osteochondromas) near the ends of long bones. The genetic abnormality results in a defect in the osteoclastic activity at the metaphyseal ends of the bone during the remodeling process in childhood or early adolescence. The metaphyses develop benign, bony outgrowths often capped by cartilage. A small number undergo neoplastic transformation.

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Numerology

  1. Chaldean Numerology

    The numerical value of exostoses, multiple hereditary in Chaldean Numerology is: 7

  2. Pythagorean Numerology

    The numerical value of exostoses, multiple hereditary in Pythagorean Numerology is: 2

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