What does ethyl loflazepate mean?
Definitions for ethyl loflazepate
ethyl loflazepate
This dictionary definitions page includes all the possible meanings, example usage and translations of the word ethyl loflazepate.
Wiktionary
ethyl loflazepatenoun
A benzodiazepine drug with anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties.
Wikidata
Ethyl loflazepate
Ethyl loflazepate is a drug which is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. In animal studies it was found to have low toxicity, although in rats evidence of pulmonary phospholipidosis occurred with pulmonary foam cells developing with long-term use of very high doses. Its elimination half-life is 51 hours - 103 hours. It's mechanism of action is similar to other benzodiazepines. Ethyl loflazepate also produces an active metabolite which is stronger than the parent compound. Ethyl loflazepate was designed to be a prodrug for descarboxyloflazepate, it's active metabolite. It is the active metabolite which is responsible for most of the pharmacological effects rather than ethyl loflazepate. The main metabolites of ethyl loflazepate are descarbethoxyloflazepate, loflazepate and 3-hydroxydescarbethoxyloflazepate. Accumulation of the active metabolites of ethyl loflazepate are not affected by those with renal failure or impairment. The symptoms of an overdose of ethyl loflazepate include sleepiness, agitation and ataxia. Hypotonia may also occur in severe cases. These symptoms occur much more frequently and severely in children. Death from therapeutic maintenance doses of ethyl loflazepate taken for 2 – 3 weeks has been reported in 3 elderly patients. The cause of death was asphyxia due to benzodiazepine toxicity. High doses of the antidepressant fluvoxamine may potentiate the adverse effects of ethyl loflazepate.
Numerology
Chaldean Numerology
The numerical value of ethyl loflazepate in Chaldean Numerology is: 7
Pythagorean Numerology
The numerical value of ethyl loflazepate in Pythagorean Numerology is: 9
Translations for ethyl loflazepate
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- этил loflazepateRussian
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"ethyl loflazepate." Definitions.net. STANDS4 LLC, 2024. Web. 19 Apr. 2024. <https://www.definitions.net/definition/ethyl+loflazepate>.
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