Definitions for episome
ˈɛp əˌsoʊmepi·some

Princeton's WordNetRate this definition:0.0 / 0 votes

1. episomenoun

   DNA that is not incorporated into the genome but is replicated together with the genome (especially in bacterial cells)

WiktionaryRate this definition:0.0 / 0 votes

1. episomenoun

   A segment of DNA that can exist and replicate either autonomously in the cytoplasm or as part of a chromosome, mainly found in bacteria.

WikipediaRate this definition:0.0 / 0 votes

1. Episome

   An episome is a special type of plasmid, which remains as a part of the eukaryotic genome without integration. Episomes manage this by replicating together with the rest of the genome and subsequently associating with metaphase chromosomes during mitosis. Episomes do not degrade, unlike standard plasmids, and can be designed so that they are not epigenetically silenced inside the eukaryotic cell nucleus. Episomes can be observed in nature in certain types of long-term infection by adeno-associated virus or Epstein-Barr virus. In 2004, it was proposed that non-viral episomes might be used in genetic therapy for long-term change in gene expression.As of 1999, there were many known sequences of DNA (deoxyribonucleic acid) that allow a standard plasmid to become episomally retained. One example is the S/MAR sequence.The length of episomal retention is fairly variable between different genetic constructs and there are many known features in the sequence of an episome which will affect the length and stability of genetic expression of the carried transgene. Among these features is the number of CpG sites which contribute to epigenetic silencing of the transgene carried by the episome.

ChatGPTRate this definition:0.0 / 0 votes

1. episome

   An episome is a genetic structure or a piece of DNA that can exist either independently in a cell or can be integrated into a cell's chromosome. They are capable of replicating independently as well as with the chromosomes of the host cell. Episomes play a significant role in bacterial conjugation, antibiotic resistance, and can also transfer genes among cells.

Matched Categories

1. • DNA

Usage in printed sourcesFrom: 

1. [["1930","7"],["1938","2"],["1942","4"],["1953","28"],["1955","3"],["1959","22"],["1960","35"],["1961","100"],["1962","75"],["1963","159"],["1964","255"],["1965","364"],["1966","108"],["1967","221"],["1968","479"],["1969","459"],["1970","278"],["1971","278"],["1972","604"],["1973","713"],["1974","303"],["1975","390"],["1976","313"],["1977","391"],["1978","185"],["1979","182"],["1980","219"],["1981","171"],["1982","84"],["1983","295"],["1984","137"],["1985","127"],["1986","173"],["1987","168"],["1988","252"],["1989","300"],["1990","196"],["1991","189"],["1992","293"],["1993","237"],["1994","233"],["1995","211"],["1996","309"],["1997","223"],["1998","195"],["1999","388"],["2000","286"],["2001","203"],["2002","364"],["2003","420"],["2004","304"],["2005","334"],["2006","305"],["2007","348"],["2008","377"]]

How to pronounce episome?

1. Alex

   US English

   David

   US English

   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

   British

   Fred

   US English

   Tessa

   South African

How to say episome in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of episome in Chaldean Numerology is: 6

2. Pythagorean Numerology

   The numerical value of episome in Pythagorean Numerology is: 1

References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=episome
2. ^ Wiktionary
   https://en.wiktionary.org/wiki/Episome
3. ^ Wikipedia
   https://en.wikipedia.org/wiki/Episome
4. ^ ChatGPT
   https://chat.openai.com
5. ^ Usage in printed sources
   https://books.google.com/ngrams/graph?content=episome