Definitions for diethylstilboestrol
di·ethyl·stil·boe·strol

Princeton's WordNetRate this definition:0.0 / 0 votes

1. diethylstilbestrol, diethylstilboestrol, stilbestrol, stilboestrol, DESnoun

   a potent estrogen used in medicine and in feed for livestock and poultry

WiktionaryRate this definition:0.0 / 0 votes

1. diethylstilboestrolnoun

   diethylstilbestrol

WikipediaRate this definition:0.0 / 0 votes

1. diethylstilboestrol

   Diethylstilbestrol (DES), also known as stilbestrol or stilboestrol, is a nonsteroidal estrogen medication, which is presently rarely used. In the past, it was widely used for a variety of indications, including pregnancy support for those with a history of recurrent miscarriage, hormone therapy for menopausal symptoms and estrogen deficiency, treatment of prostate cancer and breast cancer, and other uses. By 2007, it was only used in the treatment of prostate cancer and breast cancer. In 2011, Hoover and colleagues reported on adverse health outcomes linked to DES including infertility, miscarriage, ectopic pregnancy, preeclampsia, preterm birth, stillbirth, infant death, menopause prior to age 45, breast cancer, cervical cancer, and vaginal cancer. While most commonly taken by mouth, DES was available for use by other routes as well, for instance, vaginal, topical, and by injection. DES is an estrogen, or an agonist of the estrogen receptors, the biological target of estrogens like estradiol. It is a synthetic and nonsteroidal estrogen of the stilbestrol group, and differs from the natural estrogen estradiol in various ways. Compared to estradiol, DES has greatly improved bioavailability when taken by mouth, is more resistant to metabolism, and shows relatively increased effects in certain parts of the body like the liver and uterus. These differences result in DES having an increased risk of blood clots, cardiovascular issues, and certain other adverse effects.DES was discovered in 1938 and introduced for medical use in 1939. From about 1940 to 1971, the medication was given to pregnant women in the incorrect belief that it would reduce the risk of pregnancy complications and losses. In 1971, DES was shown to cause clear-cell carcinoma, a rare vaginal tumor, in those who had been exposed to this medication in utero. The United States Food and Drug Administration subsequently withdrew approval of DES as a treatment for pregnant women. Follow-up studies have indicated that DES also has the potential to cause a variety of significant adverse medical complications during the lifetimes of those exposed.The United States National Cancer Institute recommends children born to mothers who took DES to undergo special medical exams on a regular basis to screen for complications as a result of the medication. Individuals who were exposed to DES during their mothers' pregnancies are commonly referred to as "DES daughters" and "DES sons". Since the discovery of the toxic effects of DES, it has largely been discontinued and is now mostly no longer marketed.

ChatGPTRate this definition:0.0 / 0 votes

1. diethylstilboestrol

   Diethylstilbestrol (DES) is a synthetic form of estrogen that was developed to supplement a woman's natural estrogen production. First prescribed by doctors in 1938 for women who experienced miscarriages or premature deliveries, DES was later linked to various health risks and was banned in many countries. Today, it is most notably associated with a rare vaginal cancer found in the daughters of the women who used DES, abnormalities in the reproductive organs of both sons and daughters exposed to DES, and potential health risks to the grandchildren of DES users.

Matched Categories

1. • Estrogen

How to pronounce diethylstilboestrol?

1. Alex

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Numerology

1. Chaldean Numerology

   The numerical value of diethylstilboestrol in Chaldean Numerology is: 4

2. Pythagorean Numerology

   The numerical value of diethylstilboestrol in Pythagorean Numerology is: 6

References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=diethylstilboestrol
2. ^ Wiktionary
   https://en.wiktionary.org/wiki/Diethylstilboestrol
3. ^ Wikipedia
   https://en.wikipedia.org/wiki/Diethylstilboestrol
4. ^ ChatGPT
   https://chat.openai.com