What does dideoxyadenosine mean?

Definitions for dideoxyadenosine

Here are all the possible meanings and translations of the word dideoxyadenosine.


  1. Dideoxyadenosine

    A synthetic nucleoside analogue of deoxyadenosine and a prodrug of didanosine in which the 3' hydroxyl group on the ribose moiety is replaced by a hydrogen atom. Dideoxyadenosine competitively inhibits adenylyl cyclase, thereby reducing levels of cyclic adenosine monophosphate (cAMP). By inhibiting cAMP-mediated gene activation in tumor cells, this agent may retard tumor cell proliferation. (NCI04)

U.S. National Library of Medicine

  1. Dideoxyadenosine

    A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is an inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase. Its principal side effect is nephrotoxicity. In vivo, dideoxyadenosine is rapidly metabolized to DIDANOSINE (ddI) by enzymatic deamination; ddI is then converted to dideoxyinosine monophosphate and ultimately to dideoxyadenosine triphosphate, the putative active metabolite.


  1. Chaldean Numerology

    The numerical value of dideoxyadenosine in Chaldean Numerology is: 9

  2. Pythagorean Numerology

    The numerical value of dideoxyadenosine in Pythagorean Numerology is: 1

Images & Illustrations of dideoxyadenosine

  1. dideoxyadenosinedideoxyadenosinedideoxyadenosine


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"dideoxyadenosine." Definitions.net. STANDS4 LLC, 2018. Web. 20 Mar. 2018. <https://www.definitions.net/definition/dideoxyadenosine>.

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