What does diclofensine mean?
Definitions for diclofensine
di·clofen·sine
This dictionary definitions page includes all the possible meanings, example usage and translations of the word diclofensine.
Wikipedia
Diclofensine
Diclofensine (Ro 8-4650) was developed by Hoffmann-La Roche in the 1970s in the search for a new antidepressant. It was found that the (S)-isomer was responsible for activity. Is a stimulant drug which acts as a triple monoamine reuptake inhibitor, primarily inhibiting the reuptake of dopamine and norepinephrine, with affinities (Ki) of 16.8 nM, 15.7 nM, and 51 nM for DAT, NET, and SERT (dopamine, norepinephrine and serotonin transporters), respectively. It was found to be an effective antidepressant in human trials, with relatively few side effects, but was ultimately dropped from clinical development, possibly due to concerns about its abuse potential.Diclofensine is chemically a tetrahydroisoquinoline (THIQ) derivative, as is nomifensine.
Wikidata
Diclofensine
Diclofensine is a stimulant drug which acts as a triple monoamine reuptake inhibitor, primarily inhibiting the reuptake of dopamine and noradrenaline. It was found to be an effective antidepressant in human trials, with relatively few side effects, but was ultimately dropped from clinical development, possibly due to concerns about its abuse potential. Diclofensine is chemically a tetrahydroisoquinoline derivative, as is nomifensine.
Numerology
Chaldean Numerology
The numerical value of diclofensine in Chaldean Numerology is: 5
Pythagorean Numerology
The numerical value of diclofensine in Pythagorean Numerology is: 7
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"diclofensine." Definitions.net. STANDS4 LLC, 2024. Web. 18 Apr. 2024. <https://www.definitions.net/definition/diclofensine>.
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