Definitions for desipramine
de·sipramine

Princeton's WordNetRate this definition:0.0 / 0 votes

1. desipraminenoun

   a tricyclic antidepressant drug that activates the psychomotor system

WiktionaryRate this definition:0.0 / 0 votes

1. desipraminenoun

   A tricyclic, heterocyclic drug used to treat depression.

WikipediaRate this definition:0.0 / 0 votes

1. Desipramine

   Desipramine, sold under the brand name Norpramin among others, is a tricyclic antidepressant (TCA) used in the treatment of depression. It acts as a relatively selective norepinephrine reuptake inhibitor, though it does also have other activities such as weak serotonin reuptake inhibitory, α1-blocking, antihistamine, and anticholinergic effects. The drug is not considered a first-line treatment for depression since the introduction of selective serotonin reuptake inhibitor (SSRI) antidepressants, which have fewer side effects and are safer in overdose.

ChatGPTRate this definition:0.0 / 0 votes

1. desipramine

   Desipramine is a type of medication classified as a tricyclic antidepressant (TCA). It is commonly used to treat symptoms of depression including feelings of sadness, loss, anger, or frustration. It works by increasing the amount of specific natural substances in the brain that are required for mental balance. Desipramine can also be used to treat certain behavioural disorders, nerve pain, and attention-deficit hyperactivity disorder (ADHD).

WikidataRate this definition:0.0 / 0 votes

1. Desipramine

   Desipramine is a tricyclic antidepressant. It inhibits the reuptake of norepinephrine and to a lesser extent serotonin. It is used to treat depression, but not considered a first line treatment since the introduction of SSRI antidepressants. Desipramine is an active metabolite of imipramine. It is sold under the brand names Norpramin and Pertofrane. Along with other tricyclics, desipramine has found use in treating neuropathic pain. The mechanism of action seems to involve the activation, through norepinephrine reuptake inhibition, of descending pathways in the spinal cord that block pain signals from ascending to the brain. Desipramine is one of the most potent and selective medications in this respect. It may also be used to treat symptoms of Attention Deficit Hyperactivity Disorder, as the underproduction of norepinephrine has been increasingly linked to symptoms associated with Attention Deficit Disorder. It may also be used to treat symptoms of cocaine withdrawal.

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. Desipramine

   A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.

Matched Categories

1. • Tricyclic

How to pronounce desipramine?

1. Alex

   US English

   David

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   Mark

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   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

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   Indian

   Priya

   Indian

   Neerja

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   Zira

   US English

   Oliver

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   Wendy

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   Fred

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   Tessa

   South African

How to say desipramine in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of desipramine in Chaldean Numerology is: 3

2. Pythagorean Numerology

   The numerical value of desipramine in Pythagorean Numerology is: 5

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References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=desipramine
2. ^ Wiktionary
   https://en.wiktionary.org/wiki/Desipramine
3. ^ Wikipedia
   https://en.wikipedia.org/wiki/Desipramine
4. ^ ChatGPT
   https://chat.openai.com
5. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=desipramine