Definitions for crohn's disease
kroʊnzcrohn's dis·ease

Princeton's WordNetRate this definition:0.0 / 0 votes

1. regional enteritis, regional ileitis, Crohn's diseasenoun

   a serious chronic and progressive inflammation of the ileum producing frequent bouts of diarrhea with abdominal pain and nausea and fever and weight loss

WikipediaRate this definition:0.0 / 0 votes

1. Crohn's disease

   Crohn's disease is a type of inflammatory bowel disease (IBD) that may affect any segment of the gastrointestinal tract. Symptoms often include abdominal pain, diarrhea (which may be bloody if inflammation is severe), fever, abdominal distension, and weight loss. Complications outside of the gastrointestinal tract may include anemia, skin rashes, arthritis, inflammation of the eye, and fatigue. The skin rashes may be due to infections as well as pyoderma gangrenosum or erythema nodosum. Bowel obstruction may occur as a complication of chronic inflammation, and those with the disease are at greater risk of colon cancer and small bowel cancer.While the precise causes of Crohn's disease (CD) are unknown, it is believed to be caused by a combination of environmental, immune, and bacterial factors in genetically susceptible individuals. It results in a chronic inflammatory disorder, in which the body's immune system defends the gastrointestinal tract, possibly targeting microbial antigens. While Crohn's is an immune-related disease, it does not appear to be an autoimmune disease (in that the immune system is not being triggered by the body itself). The exact underlying immune problem is not clear; however, it may be an immunodeficiency state.About half of the overall risk is related to genetics, with more than 70 genes having been found to be involved. Tobacco smokers are twice as likely to develop Crohn's disease as nonsmokers. It also often begins after gastroenteritis. Diagnosis is based on a number of findings, including biopsy and appearance of the bowel wall, medical imaging, and description of the disease. Other conditions that can present similarly include irritable bowel syndrome and Behçet's disease.There is no known cure for Crohn's disease. Treatment options are intended to help with symptoms, maintain remission, and prevent relapse. In those newly diagnosed, a corticosteroid may be used for a brief period of time to rapidly improve symptoms, alongside another medication such as either methotrexate or a thiopurine used to prevent recurrence. Stopping smoking is recommended in people with Crohn's disease. One in five people with the disease is admitted to the hospital each year, and half of those with the disease will require surgery for the disease at some point over a ten-year period. While surgery should be used as little as possible, it is necessary to address some abscesses, certain bowel obstructions, and cancers. Checking for bowel cancer via colonoscopy is recommended every few years, starting eight years after the disease has begun.Crohn's disease affects about 3.2 per 1,000 people in Europe, North America, and the UK. It is less common in Asia and Africa. It has historically been more common in the developed world. Rates have, however, been increasing, particularly in the developing world, since the 1970s. Inflammatory bowel disease resulted in 47,400 deaths in 2015, and those with Crohn's disease have a slightly reduced life expectancy. It tends to start in young adulthood, though it can occur at any age. Males and females are equally affected.

ChatGPTRate this definition:0.0 / 0 votes

1. crohn's disease

   Crohn's disease is a chronic inflammatory bowel disease that affects the lining of the digestive tract. It is characterized by severe diarrhea, abdominal pain, fatigue, and weight loss. The inflammation caused by Crohn's disease can involve different areas of the digestive tract and can penetrate deep into the affected tissues, leading to various complications. The exact cause of Crohn's disease is unknown, although it is believed to result from a combination of genetic, immune system, and environmental factors. There is currently no known cure for Crohn's disease, but symptoms can be managed with medication, lifestyle changes, and in severe cases, surgery.

WikidataRate this definition:0.0 / 0 votes

1. Crohn's disease

   Crohn's disease, also known as Crohn syndrome and regional enteritis, is a type of inflammatory bowel disease that may affect any part of the gastrointestinal tract from mouth to anus, causing a wide variety of symptoms. It primarily causes abdominal pain, diarrhea, vomiting, or weight loss, but may also cause complications outside the gastrointestinal tract such as skin rashes, arthritis, inflammation of the eye, tiredness, and lack of concentration. Crohn's disease is caused by interactions between environmental, immunological and bacterial factors in genetically susceptible individuals. This results in a chronic inflammatory disorder, in which the body's immune system attacks the gastrointestinal tract possibly directed at microbial antigens. Crohn's disease has wrongly been described as an autoimmune disease in the past; recent investigators have described it as an immune deficiency state. There is a genetic association with Crohn's disease, primarily with variations of the NOD2 gene and its protein, which senses bacterial cell walls. Siblings of affected individuals are at higher risk. Males and females are equally affected. Smokers are two times more likely to develop Crohn's disease than nonsmokers. Crohn's disease affects between 400,000 and 600,000 people in North America. Prevalence estimates for Northern Europe have ranged from 27–48 per 100,000. Crohn's disease tends to present initially in the teens and twenties, with another peak incidence in the fifties to seventies, although the disease can occur at any age. There is no known pharmaceutical or surgical cure for Crohn's disease. Treatment options are restricted to controlling symptoms, maintaining remission, and preventing relapse. The disease was named after gastroenterologist Burrill Bernard Crohn, who, in 1932, together with two other colleagues at Mount Sinai Hospital in New York, described a series of patients with inflammation of the terminal ileum, the area most commonly affected by the illness.

Matched Categories

1. • Colitis

How to pronounce crohn's disease?

1. Alex

   US English

   David

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   Mark

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   Daniel

   British

   Libby

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   Mia

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   Karen

   Australian

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   Neerja

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   Zira

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   Wendy

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How to say crohn's disease in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of crohn's disease in Chaldean Numerology is: 2

2. Pythagorean Numerology

   The numerical value of crohn's disease in Pythagorean Numerology is: 4

Examples of crohn's disease in a Sentence

1. Alicia Rivera:

   I would actually dream about the party we would have, I would think about how amazing that would feel to see my mother go to the party instead of chemo. Alicia Rivera, Alicia Rivera, has an amazing story of survival.She was diagnosed at 18 with PC, and is now not only a survivor, but is also a nursing student and a curePC campaign participant too. It is very rare to be so young and get that diagnosis and also rare to be a PC survivor.Only 7 percent of those diagnosed with PC survive five years, and an estimated 49,000 Americans will be diagnosed this year, with more than 40,000 of them dying before the year ends, according to the American Cancer Society. I asked Rivera how she found out she had PC and how she coped with the diagnosis at 18. I was young, and so many people said to me they couldn't believe it.I have Crohn's disease, and I had my wisdom teeth extracted in October of 2011. I went into septic shock, and that's when doctors did a scan, they found the tumor, and doctors at first thought it couldn't be PC, but did a biopsy to be sure, and it came it back positive, stage 1 pancreatic cancer. Alicia Rivera said she was shocked and recalled thinking that she was going to die. Doctors performed surgery to remove half of her pancreas, taking with it her gallbladder, a bile duct, lympho nodes and half of her stomach. They then reconnected her intestines to the remaining portion of her stomach. She said she hopes her story will help others stay connected to their bodies and to be aware of potential warning signs. PC is considered the silent killer, because by the time you feel symptoms, the tumor is usually metastasized.

2. Gilaad Kaplan:

   Among smokers who are diagnosed with Crohn’s disease, quitting smoking is an action that they can take for themselves to improve their health.

3. Gilaad Kaplan:

   Among smokers who are diagnosed with Crohn’s disease, quitting smoking is an action that they can take for themselves to improve Reuters Health.

4. Wesley Black:

   I kept getting told,' oh, it's [ Irritable Bowel Syndrome ], or it's Crohn's disease, or you need to change your diet,'.

References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=crohn's disease
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Crohn'S_Disease
3. ^ ChatGPT
   https://chat.openai.com
4. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=crohn's disease