What does cofilin mean?

Definitions for cofilin

Here are all the possible meanings and translations of the word cofilin.


  1. cofilin(Noun)

    Any of a class of proteins which disassemble actin filaments


  1. Cofilin

    ADF/cofilin is a family of actin-binding proteins which disassembles actin filaments. Three highly conserved and highly identical genes belonging to this family have been described in human and mice: ⁕CFL1, coding for cofilin 1 ⁕CFL2, coding for cofilin 2 ⁕DSTN, coding for destrin, also known as ADF or actin depolymerizing factor Actin-binding proteins regulate assembly and disassembly of actin filaments. Cofilin, a member of the ADF/cofilin family is actually a protein with 70% sequence homology to ADF, making it part of the ADF/cofilin family of small ADP-binding proteins. The protein binds to actin monomers and filaments, G actin and F actin, respectively. Cofilin causes depolymerization at the minus end of filaments, thereby preventing their reassembly. The protein is known to sever actin filaments by creating more positive ends on filament fragments. Cofilin/ADF is likely to sever F-actin without capping and prefers ADP-actin. These monomers can be recycled by profilin, activating monomers to go back into filament form again by an ADP-to-ATP exchange. ATP-actin is then available for assembly.

How to pronounce cofilin?

  1. Alex
    US English

How to say cofilin in sign language?

  1. cofilin


  1. Chaldean Numerology

    The numerical value of cofilin in Chaldean Numerology is: 1

  2. Pythagorean Numerology

    The numerical value of cofilin in Pythagorean Numerology is: 5

Images & Illustrations of cofilin

  1. cofilincofilincofilincofilincofilin

Popularity rank by frequency of use



Find a translation for the cofilin definition in other languages:

Select another language:

  • - Select -
  • 简体中文 (Chinese - Simplified)
  • 繁體中文 (Chinese - Traditional)
  • Español (Spanish)
  • Esperanto (Esperanto)
  • 日本語 (Japanese)
  • Português (Portuguese)
  • Deutsch (German)
  • العربية (Arabic)
  • Français (French)
  • Русский (Russian)
  • ಕನ್ನಡ (Kannada)
  • 한국어 (Korean)
  • עברית (Hebrew)
  • Український (Ukrainian)
  • اردو (Urdu)
  • Magyar (Hungarian)
  • मानक हिन्दी (Hindi)
  • Indonesia (Indonesian)
  • Italiano (Italian)
  • தமிழ் (Tamil)
  • Türkçe (Turkish)
  • తెలుగు (Telugu)
  • ภาษาไทย (Thai)
  • Tiếng Việt (Vietnamese)
  • Čeština (Czech)
  • Polski (Polish)
  • Bahasa Indonesia (Indonesian)
  • Românește (Romanian)
  • Nederlands (Dutch)
  • Ελληνικά (Greek)
  • Latinum (Latin)
  • Svenska (Swedish)
  • Dansk (Danish)
  • Suomi (Finnish)
  • فارسی (Persian)
  • ייִדיש (Yiddish)
  • հայերեն (Armenian)
  • Norsk (Norwegian)
  • English (English)

Discuss these cofilin definitions with the community:

Word of the Day

Would you like us to send you a FREE new word definition delivered to your inbox daily?

Please enter your email address:


Use the citation below to add this definition to your bibliography:


"cofilin." Definitions.net. STANDS4 LLC, 2020. Web. 1 Apr. 2020. <https://www.definitions.net/definition/cofilin>.

Are we missing a good definition for cofilin? Don't keep it to yourself...

Free, no signup required:

Add to Chrome

Get instant definitions for any word that hits you anywhere on the web!

Free, no signup required:

Add to Firefox

Get instant definitions for any word that hits you anywhere on the web!

Nearby & related entries:

Alternative searches for cofilin:

Thanks for your vote! We truly appreciate your support.