What does clonal deletion mean?

Definitions for clonal deletion
clon·al dele·tion

This dictionary definitions page includes all the possible meanings, example usage and translations of the word clonal deletion.

Wikipedia

  1. Clonal deletion

    In immunology, clonal deletion is the removal through apoptosis of B cells and T cells that have expressed receptors for self before developing into fully immunocompetent lymphocytes. This prevents recognition and destruction of self host cells, making it a type of negative selection or central tolerance. Central tolerance prevents B and T lymphocytes from reacting to self. Thus, clonal deletion can help protect individuals against autoimmunity. Clonal deletion is thought to be the most common type of negative selection. It is one method of immune tolerance.

Freebase

  1. Clonal deletion

    Clonal deletion is a process by which B cells and T cells are deactivated after they have expressed receptors for self-antigens and before they develop into fully immunocompetent lymphocytes. It is one method of immune tolerance.

U.S. National Library of Medicine

  1. Clonal Deletion

    Removal, via CELL DEATH, of immature lymphocytes that interact with antigens during maturation. For T-lymphocytes this occurs in the thymus and ensures that mature T-lymphocytes are self tolerant. B-lymphocytes may also undergo clonal deletion.

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Numerology

  1. Chaldean Numerology

    The numerical value of clonal deletion in Chaldean Numerology is: 2

  2. Pythagorean Numerology

    The numerical value of clonal deletion in Pythagorean Numerology is: 6


Translations for clonal deletion

From our Multilingual Translation Dictionary

  • क्लोनल विलोपनHindi

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"clonal deletion." Definitions.net. STANDS4 LLC, 2023. Web. 22 Sep. 2023. <https://www.definitions.net/definition/clonal+deletion>.

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