What does cellular senescence mean?
Definitions for cellular senescence
cel·lu·lar senes·cence
This dictionary definitions page includes all the possible meanings, example usage and translations of the word cellular senescence.
Wikipedia
Cellular senescence
Cellular senescence is a phenomenon characterized by the cessation of cell division. In their groundbreaking experiments during the early 1960s, Leonard Hayflick and Paul Moorhead found that normal human fetal fibroblasts in culture reach a maximum of approximately 50 cell population doublings before becoming senescent. This process is known as "replicative senescence", or the Hayflick limit. Hayflick's discovery of mortal cells paved the path for the discovery and understanding of cellular aging molecular pathways. Cellular senescence can be initiated by a wide variety of stress inducing factors. These stress factors include both environmental and internal damaging events, abnormal cellular growth, oxidative stress, autophagy factors, among many other things.The physiological importance for cell senescence has been attributed to prevention of carcinogenesis, and more recently, aging, development, and tissue repair. Senescent cells contribute to the aging phenotype, including frailty syndrome, sarcopenia, and aging-associated diseases. Senescent astrocytes and microglia contribute to neurodegeneration.
Numerology
Chaldean Numerology
The numerical value of cellular senescence in Chaldean Numerology is: 5
Pythagorean Numerology
The numerical value of cellular senescence in Pythagorean Numerology is: 5
Translations for cellular senescence
From our Multilingual Translation Dictionary
- الشيخوخة الخلويةArabic
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"cellular senescence." Definitions.net. STANDS4 LLC, 2024. Web. 18 Apr. 2024. <https://www.definitions.net/definition/cellular+senescence>.
.svg/300px-Hayflick_Limit_(1).svg.png "cellular senescence")
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