What does capromab pendetide mean?
Definitions for capromab pendetide
capromab pen·de·tide
This dictionary definitions page includes all the possible meanings, example usage and translations of the word capromab pendetide.
Wiktionary
capromab pendetidenoun
A mouse monoclonal antibody used to image the extent of prostate cancer.
Etymology: See -pr- and -mab.
Wikipedia
capromab pendetide
Indium (111In) capromab pendetide (trade name Prostascint) is used to image the extent of prostate cancer. Capromab is a mouse monoclonal antibody which recognizes a protein found on both prostate cancer cells and normal prostate tissue. It is linked to pendetide, a derivative of DTPA. Pendetide acts as a chelating agent for the radionuclide indium-111. Following an intravenous injection of Prostascint, imaging is performed using single-photon emission computed tomography (SPECT).Early trials with yttrium (90Y) capromab pendetide were also conducted.
Wikidata
Capromab Pendetide
An immunoconjugate of the murine monoclonal antibody, 7E11-C5.3 (Capromab), conjugated to the linker-chelator, glycyl-tyrosyl-(N,-diethylenetriaminepentaacetic acid)-lysine hydrochloride (GYK-DTPA-HCl). Capromab, an IgG1 kappa immunoglobulin, binds specifically to a cytoplasmic epitope of prostate-specific membrane glycoprotein (PSMA) that is only expressed by prostatic epithelial cells (benign and malignant). Capromab pendetide can be used in diagnosis or detection of prostate cancer when labeled with Indium I-111, which emits gamma radiation and X-Ray photons that can be captured by gamma camera allowing imaging of PMSA expressing tissues.
Numerology
Chaldean Numerology
The numerical value of capromab pendetide in Chaldean Numerology is: 6
Pythagorean Numerology
The numerical value of capromab pendetide in Pythagorean Numerology is: 7
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"capromab pendetide." Definitions.net. STANDS4 LLC, 2024. Web. 24 Apr. 2024. <https://www.definitions.net/definition/capromab+pendetide>.
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