Definitions for cannabinoid receptor
cannabi·noid re·cep·tor

WiktionaryRate this definition:0.0 / 0 votes

1. cannabinoid receptornoun

   Any of several receptors, found in the central nervous system and elsewhere, that bind to cannabinoids

WikipediaRate this definition:0.0 / 0 votes

1. Cannabinoid receptor

   Cannabinoid receptors, located throughout the body, are part of the endocannabinoid system – a class of cell membrane receptors in the G protein-coupled receptor superfamily. As is typical of G protein-coupled receptors, the cannabinoid receptors contain seven transmembrane spanning domains. Cannabinoid receptors are activated by three major groups of ligands: endocannabinoids; phytocannabinoids (plant-derived such as tetrahydrocannabinol (THC) produced by cannabis); and synthetic cannabinoids (such as HU-210). All endocannabinoids and phytocannabinoids are lipophilic. There are two known subtypes of cannabinoid receptors, termed CB1 and CB2. The CB1 receptor is expressed mainly in the brain (central nervous system or "CNS"), but also in the lungs, liver and kidneys. The CB2 receptor is expressed mainly in the immune system, in hematopoietic cells, and in parts of the brain.The protein sequences of CB1 and CB2 receptors are about 44% similar. When only the transmembrane regions of the receptors are considered, amino acid similarity between the two receptor subtypes is approximately 68%. In addition, minor variations in each receptor have been identified. Cannabinoids bind reversibly and stereo-selectively to the cannabinoid receptors. Subtype selective cannabinoids have been developed which theoretically may have advantages for treatment of certain diseases such as obesity.Enzymes involved in biosynthesis/inactivation of endocannabinoids and endocannabinoid signaling in general (involving targets other than CB1/2-type receptors) occur throughout the animal kingdom.

WikidataRate this definition:0.0 / 0 votes

1. Cannabinoid receptor

   The cannabinoid receptors are a class of cell membrane receptors under the G protein-coupled receptor superfamily. As is typical of G protein-coupled receptors, the cannabinoid receptors contain seven transmembrane spanning domains. Cannabinoid receptors are activated by three major groups of ligands, endocannabinoids, plant cannabinoids and synthetic cannabinoids. All of the endocannabinoids and plant cannabinoids are lipophilic, i.e. fat soluble, compounds. There are currently two known subtypes, termed CB1 and CB2. The CB1 receptor is expressed mainly in the brain, but also in the lungs, liver and kidneys. The CB2 receptor is expressed mainly in the immune system and in hematopoietic cells. Mounting evidence suggests that there are novel cannabinoid receptors that is, non-CB1 and non-CB2, which are expressed in endothelial cells and in the CNS. In 2007, the binding of several cannabinoids to a G protein-coupled receptor in the brain was described. The protein sequences of CB1 and CB2 receptors are about 44% similar. When only the transmembrane regions of the receptors are considered, amino acid similarity between the two receptor subtypes is approximately 68%. In addition, minor variations in each receptor have been identified. Cannabinoids bind reversibly and stereo-selectively to the cannabinoid receptors. The affinity of an individual cannabinoid to each receptor determines the effect of that cannabinoid. Cannabinoids that bind more selectively to certain receptors are more desirable for medical usage.

How to pronounce cannabinoid receptor?

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Numerology

1. Chaldean Numerology

   The numerical value of cannabinoid receptor in Chaldean Numerology is: 8

2. Pythagorean Numerology

   The numerical value of cannabinoid receptor in Pythagorean Numerology is: 6

References

1. ^ Wiktionary
   https://en.wiktionary.org/wiki/Cannabinoid_Receptor
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Cannabinoid_Receptor
3. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=cannabinoid receptor