What does autoreceptor mean?
Definitions for autoreceptor
au·tore·cep·tor
This dictionary definitions page includes all the possible meanings, example usage and translations of the word autoreceptor.
Wiktionary
autoreceptornoun
A receptor, situated in the terminal of a presynaptic nerve cell, that is sensitive to neurotransmitters released by the neuron in whose membrane the autoreceptor sits.
Wikidata
Autoreceptor
An autoreceptor is a receptor located on presynaptic nerve cell membranes and serves as a part of a feedback loop in signal transduction. It is sensitive only to those neurotransmitters or hormones that are released by the neuron in whose membrane the autoreceptor sits. Canonically, a presynaptic neuron releases the neurotransmitter across a synaptic cleft to be detected by the receptors on a postsynaptic neuron. Autoreceptors on the presynaptic neuron will also detect this neurotransmitter and often function to control internal cell processes, typically inhibiting further release or synthesis of the neurotransmitter. Thus, release of neurotransmitter is regulated by negative feedback. Autoreceptors are usually G protein-coupled receptors and act via a second messenger. Autoreceptors may be located anywhere on the cell body: near the terminal at the axon, on the soma, or on the dendrites. As an example, norepinephrine released from sympathetic neurons may interact with alpha-2A and alpha-2C receptors to inhibit neurally released norepinephrine. Similarly, acetylcholine released from parasympathetic neurons may interact with muscarinic-2 and muscarinic-4 receptors to inhibit neurally released acetylcholine. An atypical example is given by the β-adrenergic autoreceptor in the sympathetic peripheral nervous system, which acts to increase transmitter release.
Numerology
Chaldean Numerology
The numerical value of autoreceptor in Chaldean Numerology is: 9
Pythagorean Numerology
The numerical value of autoreceptor in Pythagorean Numerology is: 4
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"autoreceptor." Definitions.net. STANDS4 LLC, 2024. Web. 19 Apr. 2024. <https://www.definitions.net/definition/autoreceptor>.
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